Zi-yin Shen

A prognostic analysis of patients with acute leukemia and a history of central nervous system involvement undergoing umbilical cord blood transplantation

Zi-yin Shen, Bingbing Yan, Xinyue Zhang, Yue Wu et autres

To investigate the efficacy and prognosis of umbilical cord blood transplantation (UCBT) in patients with acute leukemia (AL) and a history of central nervous system leukemia (CNSL). We retrospectively evaluated 62 patients with AL and a history of CNSL who underwent UCBT …

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[Construction of a risk prediction model for diabetes after kidney transplantation based on genome-wide association study].

Yanan Wang, Zi-yin Shen, Wei-bo Xi, Yin Zhu et autres

Family history of diabetes, preoperative TG and UA, and rs802707 are significantly associated with the occurrence of PTDM. In addition, the combination of susceptibility genes could improve the predictive ability of clinical indicators for the risk of PTDM.

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[Study on Shen Is Progressing by Keeping Pace with the Time].

Zi-yin Shen

Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine

Yanbo Ren, Jianhua Huang, Waijiao Cai, Zi-yin Shen

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Icariin, a natural flavonol glycoside, extends healthspan in mice

Suqin Zhang, Waijiao Cai, Jianhua Huang, Bin Wu et autres

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[Exploration of prolonging health span, a new medical model in the aging society].

Zi-yin Shen, Xinmin Zhang, Jianhua Huang

[Effect of compound bushen recipe on chronic fatigue syndrome in C. elegans: an experimental study].

Li-jin Nie, Waijiao Cai, Xinmin Zhang, Zi-yin Shen

OBJECTIVE: To evaluate the effect of compound bushen recipe (CBR) in improving the survival state of stress and the overall life span in C. elegans by simulating chronic fatigue syndrome (CFS) under various stress states. METHODS: The tolerance and the average survival …

Icariin promotes self-renewal of neural stem cells: An involvement of extracellular regulated kinase signaling pathway

Jianhua Huang, Waijiao Cai, Xinmin Zhang, Zi-yin Shen

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[From "different patterns in the same disease" to "analogous patterns in the same disease"].

Wenjian Wang, Zi-yin Shen

The relationship between disease in Western medicine (WM) and pattern in Chinese medicine (CM) is a key scientific issue in integrative medicine (IM). The theory of "different patterns in the same disease" has greatly promoted the development of IM and the modernization …

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Mechanisms Underlying the Antiproliferative and Prodifferentiative Effects of Psoralen on Adult Neural Stem Cells via DNA Microarray

You Ning, Jian-hua Huang, Shi-Jin Xia, Qin Bian et autres

Adult neural stem cells (NSCs) persist throughout life to replace mature cells that are lost during turnover, disease, or injury. The investigation of NSC creates novel treatments for central nervous system (CNS) injuries and neurodegenerative disorders. The plasticity and reparative potential of …

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Epimedium Flavonoids Counteract the Side Effects of Glucocorticoids on Hypothalamic-Pituitary-Adrenal Axis

Jianhua Huang, Jijun Li, Songbai Zheng, Junzhen Wu et autres

Our previous studies demonstrated that the epimedium herb, when simultaneously used with GCs, counteracted suppressive effects of GCs on the HPA axis without adverse influence on the therapeutic action of GCs. Here, total flavones were extracted from the epimedium flavonoids (EFs) and …

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The osteoprotective effect of psoralen in ovariectomy-induced osteoporotic rats via stimulating the osteoblastic differentiation from bone mesenchymal stem cells

Zhu Yang, Jian-hua Huang, Shu-fen Liu, Yong-Jian Zhao et autres

OBJECTIVE: Psoralea corylifolia extract has been reported to promote bone formation in osteoporotic animals. Psoralen (PSO), a flavonoid glycoside, as the active component of P corylifolia L, is effective in increasing new bone-forming osteoblasts in parietal bone defects. However, the effect and …

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