Chang Liu

Improved clinical efficacy of melasma with combination therapy of intense pulsed light and tranexamic acid: A retrospective analysis

Rongli Yang, Yi Fang Zhao, Jintian Luo, Chang Liu et autres

This study aimed to evaluate the efficacy and safety of intense pulsed light (IPL) therapy as a standalone treatment versus IPL therapy combined with tranexamic acid (TA) microneedling for the management of melasma. Clinical data of 29 patients with melasma were reviewed …

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Arthroscopic-assisted uni-portal spinal surgery technology in the treatment of far-out syndrome: A case report and literature review

Yuanmeng Chen, Heng Bi, Wei Zhang, Junyi Xiang et autres

This study presents the case of a male patient in his early 50s who was admitted with complaints of "recurrent low back pain accompanied by radiating pain in the left lower extremity for 3 years, with exacerbation over the past month." Physical …

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Bartonella henselae Subverts Host Cell Apoptosis by Linking Intracellular NOD2 Sensing to an AREG/EGFR Autocrine Survival Loop

Jun He, Chang Liu, Yixuan Xi, Qianrui Zeng et autres

Bartonella henselae establishes persistent infections by manipulating host cell survival, but mechanisms beyond the known type IV secretion system (T4SS)-cAMP pathway are poorly understood. Here, we delineate a novel anti-apoptotic axis in human endothelial cells hijacked by B. henselae. We found that …

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Intraoral Lesions Following Nose and Nasolabial Fold Augmentation Using Hyaluronic Acid/Poly-l-Lactic Acid Fillers: A Case Report and Literature Review

Zifei Li, Chang Liu, L-J Gu, Yu Lu et autres

Vascular complications after facial filling with hyaluronic acid/poly-l-lactic acid (HA/PLLA) composite fillers are rare. Herein, the authors report a case of vascular occlusion after nose and nasolabial fold augmentation with HA/PLLA that resulted in necrosis of the gingival papilla and unilateral hard …

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Magnetic excitations in biaxial-strain detwinned $α$-RuCl$_{3}$

Yi Li, Yanyan Shangguan, Ruixian Liu, Chang Liu et autres

The honeycomb magnet $α$-RuCl$_{3}$ has been a leading candidate for realizing the Kitaev quantum spin liquid (QSL), but its intrinsic spin dynamics have remained obscured by crystal twinning. Here we apply biaxial anisotropic strain to detwin $α$-RuCl$_{3}$ single crystals and directly visualize …

A critical role for IL-21/IL-21 receptor signaling in isoproterenol-induced cardiac remodeling

Bing Qi, Ruijun Xu, Yufei Wang, Tianwei Cheng et autres

Increased cytokine secretion from immune cells is often associated with cardiac remodeling and heart failure due to pressure overload. Several reports suggest that the IL-21/IL-21 receptor (IL-21R) signaling pathway may play a critical role in heart failure progression, but the exact mechanism …

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Targeting the STAT3/ACLY axis attenuates pulmonary inflammation but delays Mycoplasma pneumoniae clearance via citrate metabolism

Yan Yang, Xinchao Yi, Chang Liu, Qianrui Zeng et autres

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Ureaplasma urealyticum GrpE protein elicits glycolysis-mediated inflammatory responses through TLR2 in macrophages

Jing Xie, Nan Xie, Chang Liu, Min Du et autres

The pathogenesis of Ureaplasma urealyticum infection is linked to the host inflammatory response; however, the specific molecular mechanisms underlying this phenomenon have not been fully elucidated. GrpE is a chaperonin that accelerates ADP release and ATP binding to DnaK, thereby enhancing the …

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Combination of Botulinum Toxin A and Hyaluronic Acid Improved Facial Pore Enlargement Caused by Acne

Rongli Yang, Yiyang Bai, Chang Liu, Jintian Luo et autres

BACKGROUND: Acne often leads to enlarged pores on the facial skin, seriously affecting the patient's appearance. Topical and oral medications have poor efficacy in some cases of severe pore enlargement. OBJECTIVE: This study aimed to explore the clinical efficacy and safety of …

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Cryogenic Digital Image Correlation as a Probe of Strain in Iron-Based Superconductors

Ziye Mo, Chunyi Li, Wenting Zhang, Chang Liu et autres

Uniaxial strain is a powerful tuning parameter that can control symmetry and anisotropic electronic properties in iron-based superconductors. However, accurately characterizing anisotropic strain can be challenging and complex. Here, we utilize a cryogenic optical system equipped with a high-spatial-resolution microscope to characterize …

Different nursing interventions on sleep quality among critically ill patients: A systematic review and network meta-analysis

Daijin Huang, Yumei Li, Jing Ye, Chang Liu et autres

BACKGROUND: Critically ill patients in intensive care often struggle with disrupted sleep, a prevalent issue in this population. However, the question of which non-pharmacological intervention is most effective in enhancing sleep quality remains unanswered. This study was conducted to comprehensively evaluate and …

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Reactive oxygen species contribute to delirium-like behavior by activating CypA/MMP9 signaling and inducing blood-brain barrier impairment in aged mice following anesthesia and surgery

Lifang Liu, Yun Hang Hu, Yinuo Liu, De-Wen Shi et autres

Postoperative delirium (POD) is common in the elderly and is associated with poor clinical outcomes. Reactive oxygen species (ROS) and blood-brain barrier (BBB) damage have been implicated in the development of POD, but the association between these two factors and the potential …

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