Accès ouvert
2025
article
OpenAlex
Wenping Luo, Guodong Wang, Shaojun Chen, Zhe Wang et autres
Objective: To compare the effectiveness and safety of External Beam Radiotherapy (EBRT) versus Portal Vein Stent Implantation (PVSI) when combined with local interventional therapy and TKI plus ICIs in patients with hepatocellular carcinoma (HCC) and portal vein tumor thrombus (PVTT), providing real-world …
cn
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Accès ouvert
2025
article
OpenAlex
Chuanhua Zhao, Yanqiao Zhang, Gang Wang, Jinfang Zheng et autres
We aimed to assess the tolerability and efficacy of finotonlimab (an anti-programmed cell death protein-1 antibody) in combination with SCT510, a bevacizumab biosimilar, versus sorafenib in unresectable advanced HCC. This randomized phase 2 and 3 study (ClinicalTrials.gov, NCT04560894; Chinadrugtrials.org.cn, CTR20201976 and CTR20201974) …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Qingqing Pang, Wenping Luo, Shaojun Chen, Hua Zhou et autres
Objective: To evaluate the safety and short-term clinical efficacy of drug-loaded polyvinyl alcohol microspheres transarterial chemoembolization (D-TACE) in the treatment of unresectable large liver carcinoma with sequential double-needle water-cooled circulating radiofrequency ablation (D-RFA). Methods: A retrospective analysis was performed for patients with …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Ziliang Qin, Xinmiao He, Chao Chen, Shaojun Chen et autres
Seneca Valley virus (SVV) infection has recently disseminated across pig farms in Canada, America, and China. The SVV has been identified in humans, rodents, and houseflies. Although cross-species transmission events may lead to limited subsequent transmission, sustained outbreaks have been observed in …
cn
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Accès ouvert
2024
article
OpenAlex
Ziwei Yan, Lai Jiang, Gang Li, Kailai Xia et autres
To evaluate the efficacy of neuronavigation-assisted stereotactic drilling drainage compared with that of craniotomy in the treatment of massive intracerebral haemorrhage (ICH) in elderly patients. This was a randomized, controlled, blind endpoint clinical study. Elderly patients with massive ICH treated at our …
cn
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Shaojun Chen, Zida Nai, Ziliang Qin, Gang Li et autres
Lacticaseibacillus is one of the predominant microorganisms in gut from human and animal, and the lacticaseibacillus have effective applications against the viral diarrhea of piglets in the farm. However, the function and the concrete cell single pathways of the active ingredient from …
cn, mn
(code pays fourni par la source)
2023
article
OpenAlex
Shaojun Chen, Xiuwu Pan, Liang Zhang, Xingang Cui et autres
Renal cell carcinoma (RCC) is one of the most common urological cancers in adults. Forkhead box k1 (FOXK1) is a transcription factor involved in the progression of various malignant tumors. In this study, we aimed to investigate the expression and roles of …
cn
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Accès ouvert
2023
article
OpenAlex
Shaojun Chen, Xinmiao He, Ziliang Qin, Gang Li et autres
Lactobacillus casei (L. casei) has four possible mechanisms: antimicrobial antagonism, competitional adhesion, immunoregulation, and the inhibition of bacterial toxins. To delineate the metabolic reactions of nucleotides from L. casei that are associated with mechanisms of inhibiting pathogens and immunoregulation, we report that …
cn
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Gang Li, Shaojun Chen, Jing Han, Wanxi Pan et autres
Objective: To investigate the safety and outcomes of endovascular embolization and craniotomy clipping in the treatment of cerebral aneurysms. Methods: We collected the clinical data of 106 patients with cerebral aneurysm who underwent surgical treatment (endovascular embolization, Group-A, n=55; craniotomy clipping, Group-B, …
cn
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Accès ouvert
2023
article
OpenAlex
Xin Huang, Ziwei Yan, Lai Jiang, Shaojun Chen et autres
Objective The aim of this study was to evaluate the effects of stereotactic minimally invasive puncture with different catheter placement positions when combined with urokinase thrombolysis for the treatment of small- and medium-volume basal ganglia hemorrhage. Our goal was to identify the …
cn
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Accès ouvert
2023
preprint
OpenAlex
Shaojun Chen, Gang Li, Jun Bao, Ziliang Qin et autres
Abstract Background Lactobacillus casei had four possible probiotic roles, such as antimicrobial antagonism, competitional adhesion, immunoregulation and inhibition of bacterial toxin. The complex environment of gut microbe blocked to explore the antimicrobial scheme through genetics, metabolomics, proteomics, and signal transduction wth Lactobacillus …
cn, my
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Shaojun Chen, Zida Nai, Ziliang Qin, Gang Li et autres
Abstract Lactobacillus is one of the predominant microorganisms in gut from human and animal, and the lactobacillus have effective applications against the viral diarrhea of piglets in the farm. However, the function and the concrete cell single pathways of the active ingredient …
cn, my
(code pays fourni par la source)