Wen Li

Sequence-Dependent Assembly and Photoregulated Antibacterial Activity of Azobenzene-Modified Ultrashort Peptides

Yi Cheng, Shuaishuai Nie, Xueliang Cheng, Wen Li

Abstract Ultrashort peptides are attractive supramolecular building blocks for constructing ordered nanostructures and bioactive materials. In this study, azobenzene-modified amphiphilic dipeptides and tripeptides were designed to investigate the cooperative effects of hydrophobic residues and photoresponsiveness on self-assembly behavior and antibacterial activity. Structural …

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Polyoxometalates‐Driven Oxidative Polymerization of Thioctic Acid and Synchronized Noncovalent Cross‐Linking to Generate High‐Strength and Colorimetric Adhesives

Jun Fang, Xiao Xiao, Pengyuan Ye, Yuebo Meng et autres

ABSTRACT Polythioctic acid (PTA) and its derivatives carrying disulfide bonds within the polymer backbone have emerged as leading candidates for yielding degradable and recyclable polymers. However, their development has been impeded by the persistent trade‐off between degradability and mechanical strength, as well …

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Polyoxometalates‐Driven Oxidative Polymerization of Thioctic Acid and Synchronized Noncovalent Cross‐Linking to Generate High‐Strength and Colorimetric Adhesives

Jun Fang, Xiao Xiao, Pengyuan Ye, Yuebo Meng et autres

Polythioctic acid (PTA) and its derivatives carrying disulfide bonds within the polymer backbone have emerged as leading candidates for yielding degradable and recyclable polymers. However, their development has been impeded by the persistent trade-off between degradability and mechanical strength, as well as …

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Intrinsic Charge-Shielding Effects of Bacteria Promote Rapid On-Surface Assembly of Random-Coil Oligopeptides for Enhanced Antibacterial Activity

Yi Cheng, Shuaishuai Nie, Hongyun Zhao, Jiayi Sun et autres

Bacteria-induced assembly of cationic oligopeptides via a charge shielding mechanism represents a promising strategy for improving the antibacterial capacity of oligopeptides. However, the impact of amino acid residues, sequence encoding, and charges on antibacterial activity remains to be more clearly elucidated. We …

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Self‐Assembling Nano‐Antimicrobial Oligopeptides With Dual Offense–Defense Functions for Synchronously Achieving High Activity and Biosafety

Hongyun Zhao, Ye Tian, Runpeng Liu, Huimei Yu et autres

ABSTRACT Self‐assembling nano‐antimicrobial peptides (nano‐AMPs) hold significant promise for addressing bacterial resistance, yet the persistent activity–biocompatibility paradox remains a major scientific challenge. Here, we present an “integrated offense‒defense” strategy in which binding to mammalian cells is inhibited (defense) but bacterial membrane insertion …

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Self‐Assembling Nano‐Antimicrobial Oligopeptides With Dual Offense–Defense Functions for Synchronously Achieving High Activity and Biosafety

Hongyun Zhao, Ye Tian, Runpeng Liu, Huimei Yu et autres

ABSTRACT Self‐assembling nano‐antimicrobial peptides (nano‐AMPs) hold significant promise for addressing bacterial resistance, yet the persistent activity–biocompatibility paradox remains a major scientific challenge. Here, we present an “integrated offense‒defense” strategy in which binding to mammalian cells is inhibited (defense) but bacterial membrane insertion …

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“Strong‐Weak” Coupled Bidirectional Anchoring Strategy Enables Protein Hydrogel to Synchronize Tissue Adhesion and Deformation Tolerance for Bladder Sealing

Guang Wen, Yulong Dong, Xinquan Gu, He Zhao et autres

Abstract Bioadhesives face significant challenges in achieving both wet tissue adhesion and deformation tolerance for bladder sealing. This study presents a “covalent/non‐covalent” coupled bidirectional anchoring strategy to develop a high‐performance protein‐based Janus patch. The patch comprises a deformable hydrogel bottom layer (composed …

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Template-Directed Growth of a 3D Hierarchical Structure of Well-Aligned Bimetallic MOF Arrays for High-Efficiency Electrocatalytic Air Sterilization

Liting Dong, Shougang Chen, Zhipeng Zhao, Xiao Sun et autres

Bimetallic MOF array has more catalytic active sites, better conductivity and water stability, which shows high efficiency in air disinfection and protects public health. To address increasing concerns regarding environmental air quality, it is highly desirable to develop low-cost and high-efficiency air-sterilization …

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A Hyperbranched Copolymer as High-Temperature and Salt-Resistance Fluid Loss Reducer for Water-Based Drilling Fluids: Preparation, Evaluation, and Mechanism Study

Jian Li, Junhao Fan, Jinsheng Sun, Zhaoyang Wang et autres

Summary In the high-temperature and high-salt environment of deep and ultradeep wells, conventional linear polymer fluid loss reducers for drilling fluids have high viscosity and are prone to conformational changes (such as curling, crosslinking, and degradation), posing significant challenges to the control …

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Emerging Poorly Crystalline Molybdenum–Sulfur–Oxygen Ternary Compound for Aqueous Zinc-Ion Batteries

Sai Wang, Jiayu Liang, Zeyu Li, Wen Li

This study reports a novel poorly crystalline molybdenum–sulfur–oxygen ternary compound (PMoSO) synthesized via a simple solution-based approach, exhibiting exceptional zinc-ion storage performance across a wide temperature range from 25 to −60 °C. At room temperature (25 °C), PMoSO exhibits an initial charge …

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Sustainable and robust hot melt adhesives via non-covalent cross-linking of arginine and short-chain fatty acids

Yuebo Meng, Xue Wang, Jun Fang, Guang Wen et autres

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Application of Monte Carlo’s Method in The Study of Fluorescence Efficiency in Relation to Target Angle

Derong Dai, XinE Zhou, Siming Guo, Taiwei Shi et autres

The K-fluorescence X-ray facility of the Chinese National Institute of Metrology was originally designed to take advantage of the good fluorescence monochromaticity to calibrate the detector on the ground. The target angle of a conventional fluorescence device is set to 45 degrees, …

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