2026
article
OpenAlex
Vignan Yogendrakumar, Justin YH Phung, Hannah Johns, Leonid Churilov et autres
BACKGROUND: Tenecteplase has been previously evaluated in large- and medium-sized vessel occlusion subgroups, but its effectiveness in more distal occlusions, particularly those involving the distal middle cerebral artery branches or the anterior cerebral artery and posterior cerebral artery territories, and across varying …
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2025
article
OpenAlex
Yiran Zhang, Brian Buck, Philip A. Barber, Kausik Chatterjee et autres
Importance: Outcomes following intravenous thrombolysis for minor ischemic stroke may vary based on the presence of disabling deficits. Objective: To determine whether intravenous tenecteplase improves outcomes according to US National Institutes of Health Stroke Scale (NIHSS) score-based definitions of pretreatment disabling deficits. …
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2025
article
OpenAlex
Amy Yu, Shabnam Vatanpour, Aravind Ganesh, Thalia S. Field et autres
BACKGROUND: In this subanalysis of the TEMPO-2 (Tenecteplase Versus Standard of Care for Minor Ischaemic Stroke With Proven Occlusion) trial, a randomized clinical trial comparing tenecteplase and nonthrombolytic control in patients with minor stroke and symptomatic intracranial occlusion, we investigated sex differences …
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2024
article
OpenAlex
Shelagh B. Coutts, Sandeep Ankolekar, Ramana Appireddy, Juan F. Arenillas et autres
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