CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV
Roland Immler, Katrin Nussbaumer, Axel Doerner, Omar El Bounkari et autres
Eosinophil recruitment is a pathological hallmark of many allergic and helminthic diseases. Here, we investigated chemokine receptor CCR3-induced eosinophil recruitment in sialyltransferase St3gal4 −/− mice. We found a marked decrease in eosinophil extravasation into CCL11-stimulated cremaster muscles and into the inflamed peritoneal …
de, us (code pays fourni par la source)
13 citations
Proceedings of the National Academy of Sciences