Uri Flegler Vieira-Machado

Resgate da subjetividade para a formação de profissionais para o cuidado farmacêutico: relato de experiência de uma disciplina de autoetnografia

Clarissa Campos Barbosa de Castro, Jéssica Aline Silva Soares, Uri Flegler Vieira-Machado, Poliana Alves da Luz Fonseca et autres

Introdução: O cuidado farmacêutico exige uma prática clínica centrada na pessoa, na qual o paciente deve ser assistido sob a perspectiva biopsicossocial, com atenção às suas experiências subjetivas com o uso de medicamentos e plantas medicinais. Assim, para que o(a) farmacêutico(a) possa …

Colaboração Interinstitucional para a Transformação da Educação e da Prática Farmacêutica no Sistema Único de Saúde

Jéssica Aline Silva Soares, Emmanuelle Eduarda Nery Vieira, Uri Flegler Vieira-Machado, Ana Emília Oliveira Ahouagi et autres

Introdução: A mudança, embora seja uma constante na realidade humana, pode apresentar-se como um grande desafio. Transformar o exercício profissional e a educação de uma das profissões mais antigas na área da saúde, como a Farmácia, exige um esforço colaborativo, resiliente e …

Identification and Characterization of Alamandine-(1-5), a New Component of the Renin-Angiotensin System

Robson A.S. Santos, Melissa Tainan Silva Dias, Amanda de Sá Martins de Bessa, Carolina Fonseca de Barros et autres

BACKGROUND: The renin-angiotensin system comprises a biochemical cascade that hydrolyzes angiotensinogen into several different bioactive peptides, which can activate different receptors, promoting plenty of specific effects. This study aimed to evaluate the presence of the putative product of alamandine, the pentapeptide Ala-(1-5) …

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Chemotherapy-induced neuropathy in monomethyl Auristatin E treatment: prevention by lithium

Matheus F. Itaborahy, Isadora Zhong Liang Ferreira Feng, Uri Flegler Vieira-Machado, Izabela Boueri da Silveira et autres

BACKGROUND: The increasing number of cancer survivors, thanks to improved cancer treatments, has escalated the prevalence of adverse effects, especially chemotherapy-induced peripheral neuropathy (CIPN) and chemotherapy-induced cognitive impairment (CICI). New drug classes, including antibody-drug conjugates (ADCs), are being developed to target cancer …

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Abstract P211: Angiotensin-(2-7): A novel antihypertensive peptide of the renin-angiotensin-system

Carolina Barros, Kamylle Silva Ferraz, Uri Flegler Vieira-Machado, Isadora Zhong Liang Ferreira Feng et autres

Recently, it has been described that acetyl-angiotensin (2-7)-amide (Ac-Ang-(2-7)-NH2) is a potent ACE inhibitor. In addition, the putative endogenous peptide angiotensin-(2-7) was also reported to be an ACE inhibitor. Here we tested the effect of Ang-(2-7) in blood pressure (BP) and isolated …

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Identification and characterization of alamandine-(1-5), a new component of the Renin-Angiotensin System with unique properties

Melissa Tainan Silva Dias, Sthefanie Chaves de Almeida Gonçalves, Filipe Alex da Silva, Lucas Rodrigues‐Ribeiro et autres

ABSTRACT The renin-angiotensin system (RAS) comprises a biochemical cascade that hydrolyzes angiotensinogen into several different bioactive peptides, which can activate different receptors promoting plenty of specific effects. The aim of this study was to evaluate the presence of the putative product of …

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The Role of Centro De Estudos Do Medicamento (Cemed) in Health Informatics and Education: a Teaching Experience Report

Uri Flegler Vieira-Machado, Laura Beatriz Fonseca, Helena Sclauser Basílio, Ághata Scarlett de Assis Vieira et autres

The Fourth Brazilian Congress of Pharmacotherapy and Clinical Pharmacy showcases Brazil's role within the vibrant and evolving community of pharmacotherapy and clinical pharmacy in Latin America. This volume offers a window into Brazil's ongoing contributions as part of a collective Latin American …