Paola Negrete‐Rodríguez

Citomegalovirus Serology and Response to Autologous Haematopoietic Stem Cell Transplantation in Persons With Multiple Sclerosis

Luis Enrique Hamilton‐Avilés, Moisés Manuel Gallardo‐Pérez, Miranda Melgar‐de‐la‐Paz, Paola Negrete‐Rodríguez et autres

Multiple sclerosis (MS) is a prevalent autoimmune disease with increasing incidence in certain populations, and autologous haematopoietic stem cell transplantation (aHSCT) represents an important therapeutic option. Cytomegalovirus (CMV) has been implicated in the pathophysiology of several immune-mediated conditions, prompting evaluation of its …

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Low iron transferrin saturation might be beneficial in the outcome of autologous transplant in multiple sclerosis

Miranda Melgar‐de‐la‐Paz, Moisés Manuel Gallardo‐Pérez, Luis Enrique Hamilton‐Avilés, Paola Negrete‐Rodríguez et autres

Research data are not shared.

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Evaluation of the Effect of Autologous Hematopoietic Stem Cell Transplant on Symptom Severity Using Msws-12, Amsq and Symptomscreen in Multiple Sclerosis Patients.

Gloria Erendy Cruz‐Pérez, Moisés Manuel Gallardo‐Pérez, Danae García‐Vélez, Miranda Melgar‐de‐la‐Paz et autres

INTRODUCTION Multiple sclerosis (MS) is a complex inflammatory, demyelinating, and neurodegenerative disease of the central nervous system that causes a whole spectrum of neurological disorders as well as patient's perception of an abnormal physical, emotional or cognitive state, associated with a profound …

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The Quality of Life of Persons with Multiple Sclerosis Improves after Autologous Haematopoietic STEM Cell Transplantation

Olivia Lira‐Lara, Moisés Manuel Gallardo‐Pérez, Miranda Melgar‐de‐la‐Paz, Paola Negrete‐Rodríguez et autres

INTRODUCTION Multiple sclerosis (MS) is a complex inflammatory, demyelinating and neurodegenerative disease of the central nervous system that causes a whole spectrum of neurological disorders as well as patient's perception of an abnormal physical, emotional or cognitive state, associated with a profound …

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Are Neutrophil / Lymphocyte Ratio and Platelet / Lymphocyte Ratio Biomarkers of the Response to Autologous Hematopoietic Stem Cell Transplantation in Persons with Multiple Sclerosis?

Guillermo Ocaña‐Ramm, Moisés Manuel Gallardo‐Pérez, Javier Garcés‐Eisele, Daniela Sánchez‐Bonilla et autres

Introduction Autologous hematopoietic stem cell transplantation (aHSCT) is a therapeutic option for patients with multiple sclerosis (MS), by “resetting” the immunological system to baseline functions. There are currently no useful biomarkers that predict the response to the transplant. The neutrophil to lymphocyte …

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Acute Promyelocytic Leukemia Can be Fully Treated on an Outpatient Basis: A Single Institution's 30-Year Experience

Guillermo J. Ruíz‐Argüelles, Danae García‐Vélez, Moisés Manuel Gallardo‐Pérez, Gloria Erendy Cruz‐Pérez et autres

Background Acute promyelocytic leukemia (APL) is the most frequent variant of acute myelogenous leukemia (AML) in Mexico and other Latin American countries; advances in its treatment have turned this once very aggressive type of leukemia into the most curable. The development of …

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Acute promyelocytic leukemia can be fully treated on an outpatient basis: a single institution experience

Danae García‐Vélez, Moisés Manuel Gallardo‐Pérez, Gloria Erendy Cruz‐Pérez, Miranda Melgar‐de‐la‐Paz et autres

The objective of this study is to explore the possibility of treating APL patients fully as outpatients. A total of 21 consecutive APL patients were identified over 30 years in the Centro de Hematología y Medicina Interna de Puebla, at Clínica Ruiz, …

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Burden in Multiple Sclerosis Caregivers: A Single-Center Experience

Miranda Melgar‐de‐la‐Paz, Moisés Manuel Gallardo‐Pérez, Luis Enrique Hamilton‐Avilés, Paola Negrete‐Rodríguez et autres

Objective: To analyze the relation between Zarit and the MSQol-54 scales in caregivers and patients with multiple sclerosis (MS). Methods: Our study included 167 caregivers of 153 patients with MS in a single center, from July 2021 to December 2023. Results: Evaluation …

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The Latin-American Experience in POEMS Syndrome: A Study of the GELAMM (Grupo de Estudio Latinoamericano de Mieloma Múltiple)

Moisés Manuel Gallardo‐Pérez, Paola Negrete‐Rodríguez, Morie A Gertz, Camila Peña et autres

INTRODUCTION: POEMS syndrome is a rare paraneoplastic syndrome caused by an underlying plasma cell disorder. The acronym refers to the following features: polyradiculoneuropathy, organomegaly, endocrinopathy, monoclonal paraproteinemia, and skin changes. METHODS: The study was conducted at 24 hematological centers across 8 Latin-American …

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Prevalence and Consequences of a Delayed Diagnosis in Multiple Myeloma: A Single Institution Experience

Paola Negrete‐Rodríguez, Moisés Manuel Gallardo‐Pérez, Olivia Lira‐Lara, Miranda Melgar‐de‐la‐Paz et autres

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Neutrophil to lymphocyte ratio and systemic immune‐inflammatory index as markers of response to autologous hematopoietic stem cell transplantation in persons with multiple sclerosis

Guillermo Ocaña‐Ramm, Moisés Manuel Gallardo‐Pérez, Solón Javier Garcés‐Eisele, Daniela Sánchez‐Bonilla et autres

INTRODUCTION: Biomarkers that help to evaluate the immune system and could be useful in multiple sclerosis (MS) are the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and systemic immune-inflammatory index (SII). The objective of this work is to evaluate …

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Prevalence of the t(11; 14)(q13; q32) immunoglobulin H/CCND1 in Mexican mestizos with multiple myeloma: A single institution experience

Olivia Lira‐Lara, Moisés Manuel Gallardo‐Pérez, Solón Javier Garcés‐Eisele, Virginia Reyes‐Núñez et autres

Abstract: BACKGROUND: Multiple myeloma (MM) is a hematologic malignancy resulting from clonal proliferation of plasma cells in which significant heterogeneity has been demonstrated, both cytogenetically and molecularly. Translocation (11;14)(q13;q32), involving the CCND1 gene, has been described as the most common one, its …

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