Genotoxin-producing Salmonella enterica induces tissue-specific types of DNA damage and DNA damage response outcomes
María López Chiloeches, Anna Bergonzini, Océane C. B. Martin, Nicole Bergstein et autres
Introduction Typhoid toxin-expressing Salmonella enterica causes DNA damage in the intestinal mucosa in vivo, activating the DNA damage response (DDR) in the absence of inflammation. To understand whether the tissue microenvironment constrains the infection outcome, we compared the immune response and DDR …
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16 citations
Frontiers in Immunology