Profil bibliographique

Samantha Rokey

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

5Publications signalées

19Citations signalées

1Affiliations récentes

Institutions déclarées

Domaines associés

Down syndrome and intellectual disability researchLung Cancer Treatments and MutationsWnt/β-catenin signaling in development and cancerPI3K/AKT/mTOR signaling in cancerUbiquitin and proteasome pathways

Publications récentes

Accès ouvert 2026 preprintOpenAlex

Dyrk1a inhibition with the Novel Compound DYR533: A Cross-Disease Therapeutic Strategy Targeting Amyloidosis, Tau Pathogenesis, and Neuroinflammation

Samantha K Bartholomew, Julie Turk, Wendy Winslow, Chris Foley et autres

1 citationbioRxiv (Cold Spring Harbor Laboratory)

2025 conference-abstractOpenAlex

Abstract 6979: Development of orally bioavailable multi-targeted inhibitors of Wnt signaling for the treatment of colorectal cancer

Sean Brendan Ginn, Samantha Rokey, Alessandra Fistrovich, Aidan McMahon et autres

0 citationsCancer Research

Accès ouvert 2025 preprintOpenAlex

Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signaling

Vasudha Tandon, Alessandra Fistrovich, Joaquina Nogales, Febe Ferro et autres

0 citationsbioRxiv (Cold Spring Harbor Laboratory)

Accès ouvert 2024 articleOpenAlex

Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B

Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley et autres

17 citationsJournal of Medicinal Chemistry

2023 articleOpenAlex

A novel DYRK1a inhibitor, DYR533, reduces tau pathology and TNF alpha in the 3xTg‐AD and PS19 mouse models

Samantha K Bartholomew, Wendy Winslow, Samantha Rokey, Christopher Hulme et autres

1 citationAlzheimer s & Dementia

Notice OpenAlex

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