Natasha Varghese Isaac

Failure Modes in Ilizarov Limb Salvage: A Narrative Review of Technical, Biological, Patient-related and Systemic Determinants

Saran JSRG, Natasha Varghese Isaac, Syed Abdul Mubdi, Ajai Patil et autres

Aim and background: The Ilizarov circular external fixator remains a cornerstone of limb salvage for infected non-unions, segmental bone defects, limblength discrepancies and severe deformities.Despite consistently high union rates, treatment is prolonged and associated with a substantial burden of Paley-defined problems, obstacles …

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Posterolateral fixation of posterior malleolar fractures: Reduction quality and mid-term outcomes in complex ankle injuries

J S R G Saran, Ajoy S. M, RAHUL P, Inderjit Singh et autres

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Meniscal preservation beyond 40 – outcomes of arthroscopic repair of chronic bucket-handle tears

Natasha Varghese Isaac, Goutham Gowdara, J. R. Anand, J S R G Saran et autres

This case series evaluated the outcomes of arthroscopic repair in five patients aged over 40 years with chronic medial bucket-handle meniscal tears, with a mean symptom duration of nine months. All patients demonstrated intraoperative adhesions (60% classified as major) along with grade …

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Does geography influence wound healing following revision total hip arthroplasty for periprosthetic joint infection? A retrospective comparative cohort study

J S R G Saran, J. R. Anand, Rakshith P. Uttam, Natasha Varghese Isaac et autres

Background: Periprosthetic joint infection (PJI) after revision total hip arthroplasty (THA) poses significant wound-management challenges. Outcomes following vacuum-assisted closure (VAC) therapy vary and may be influenced by regional microbiology and host soft-tissue characteristics. Methods: This retrospective comparative cohort study (2019-2025) included adults …

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Neuraxial versus general anaesthesia in total joint arthroplasty: perioperative outcomes, selection bias and contextual decision-making: a narrative review

Natasha Varghese Isaac, Rakshith P. Uttam, Syed Abdul Mubdi, J S R G Saran et autres

Total hip and knee arthroplasty volumes are increasing worldwide and neuraxial anaesthesia is often preferred over general anaesthesia because of perceived perioperative benefits. However, much of the available evidence is derived from observational studies and may be influenced by selection bias and …

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Mapping Foot and Ankle Psoriatic Arthritis: Global Trends, Regional Variations, and the Indian Experience: A Narrative Review

Saran JSRG, Goutham G, Jampuram Sethumadhava Varma, Natasha Varghese Isaac

Narrative review healthcare settings.A clearer understanding of these factors can support earlier identification and more effective, patient-centered care for individuals living with PsA. IntroductIonPsoriatic arthritis (PsA) is a chronic inflammatory disorder that arises in a subset of individuals with psoriasis, characterized by …

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Simultaneous Bilateral Total Knee Arthroplasty: A Cautionary Perspective on Fat Embolism Risk despite Technical Simplification

J. S. R. G. Saran, Jampuram Sethumadhava Varma, Natasha Varghese Isaac, J. R. Anand

Sir, We read with interest the article by Wasfy et al. reporting outcomes of 120 simultaneous bilateral total knee arthroplasties (simBTKA) performed using patient-specific templating (PST) with unilateral tibial stems or revision implants.[1] The authors demonstrated excellent functional improvement (mean Knee Society …

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To resurface or not? Early pain and functional outcomes following primary total knee arthroplasty

Durai Anand, J. S. R. G. Saran, Jampuram Sethumadhava Varma, Natasha Varghese Isaac et autres

Abstract Introduction: Total knee arthroplasty (TKA) is an effective treatment for advanced knee osteoarthritis; however, the optimal management of the patellofemoral joint remains controversial. While patellar resurfacing may reduce anterior knee pain and reoperation rates, it is also associated with procedure-specific risks. …

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Concealed cannabis use and adverse outcomes after lower-limb arthroplasty in a narcotic drugs and psychotropic substances -constrained setting: A case series

J. S. R. G. Saran, R. Venkatesan, Natasha Varghese Isaac, Chetan Hiremath et autres

Abstract Background: Preoperative cannabis use disorder is an established independent risk factor for adverse outcomes after total hip and knee arthroplasty in legalized settings, where disclosure is reliable. In India, enforcement under the Narcotic Drugs and Psychotropic Substances (NDPS) Act promotes stigma …

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Frailty assessment tools and their predictive value in preoperative evaluation for general surgery: a narrative review

Swizel Ann Cardoso, Jenisha Suyambu, Aamir Amin, Javed Iqbal et autres

The world’s population is ageing rapidly, with projections suggesting a significant increase in the elderly demographic over the next few decades. This shift is likely to result in long periods of infirmity and frailty, thus escalating healthcare demands. Frailty has been investigated …

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The Effect of American Society of Anesthesiologists Score and Operative Time on Surgical Site Infection Rates in Major Abdominal Surgeries

Rayees Ahmad Bhat, Natasha Varghese Isaac, Jeffin Joy, Deepika Chandran et autres

BACKGROUND: The objective of this study was to evaluate the influence of two crucial variables, the American Society of Anesthesiologists (ASA) score and operative time, on the occurrence of surgical site infections (SSIs) in the context of major abdominal surgical procedures. METHODOLOGY: …

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Future of Artificial Intelligence in Surgery: A Narrative Review

Aamir Amin, Swizel Ann Cardoso, Jenisha Suyambu, Hafiz Abdus Saboor et autres

Artificial intelligence (AI) is the capability of a machine to execute cognitive processes that are typically considered to be functions of the human brain. It is the study of algorithms that enable machines to reason and perform mental tasks, including problem-solving, object …

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