María del Mar Ras-Jiménez

Iron Matters: Comparative Impact of Beta-Adrenergic Stimulation and Iron Chelation on Cardiac Iron Metabolism and Mitochondrial Function

Josep Francesch-Manzano, Marta Tajes, Raúl Ramos-Polo, Cristina Enjuanes et autres

Iron deficiency (ID) is frequent in patients with heart failure (HF) and is correlated with adverse outcomes, yet its involvement in HF pathophysiology is not fully understood. Hyperactivity of the sympathetic nervous system (SNS) is the central feature of HF. We aimed …

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Serum Growth Differentiation Factor 15 (GDF15) Levels Reflect Ischemic Etiology in Heart Failure Patients with Iron Deficiency: A Cross-Sectional Study

Marta Tajes, María del Mar Ras-Jiménez, Josefa Girona, Raúl Ramos-Polo et autres

Heart failure (HF), particularly of an ischemic etiology, is steadily increasing worldwide. Non-anemic iron deficiency (ID) is highly prevalent among HF patients, and it has been related to worse outcomes. Growth differentiation factor 15 (GDF15) has been related to atherosclerotic cardiovascular (CV) …

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Myocardial Performance Improvement After Iron Replacement in Heart Failure Patients: The IRON-PATH II Echo-Substudy

Raúl Ramos-Polo, María del Mar Ras-Jiménez, María del Carmen Basalo Carbajales, Sílvia Jovells-Vaqué et autres

Background: Iron deficiency (ID) is a commonly seen comorbidity in heart failure (HF) patients. It is often associated with a poor prognosis and impaired physical capacity. The functional limitations linked to ID may lead to cardiac function abnormalities. The functional limitations linked …

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Myocardial performance improvement after iron replacement in heart failure patients: The IRON-PATH II echo-substudy

Raúl Ramos-Polo, María del Mar Ras-Jiménez, María del Carmen Basalo Carbajales, Sílvia Jovells-Vaqué et autres

Abstract Iron deficiency (ID) is a prevalent comorbidity in heart failure (HF) patients associated with poor prognosis and impaired physical capacity. Functional limitations linked to ID may be related to cardiac function abnormalities, which could be reversible with iron repletion. Some echocardiographic …

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6101-12. DIFERENTE PERFIL PROTEÓMICO EN SANGRE DE PACIENTES CON INSUFICIENCIA CARDIACA EN FUNCIÓN DE LA PRESENCIA DE DÉFICIT DE HIERRO

Josep Francesch Manzano, Marta Tajes Orduña, Raúl Ramos-Polo, María del Mar Ras-Jiménez et autres

Prognostic Role of Tissue Iron Deficiency Measured by sTfR Levels in Heart Failure Patients without Systemic Iron Deficiency or Anemia

Raúl Ramos-Polo, María del Mar Ras-Jiménez, Josep Francesch Manzano, Sílvia Jovells-Vaqué et autres

Background. Iron deficiency (ID) is a significant, high-prevalence comorbidity in chronic heart failure (HF) that represents an independent predictor of a worse prognosis. However, a clear-cut diagnosis of ID in HF patients is not assured. The soluble transferrin receptor (sTfR) is a …

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Soluble Transferrin Receptor as Iron Deficiency Biomarker: Impact on Exercise Capacity in Heart Failure Patients

María del Mar Ras-Jiménez, Raúl Ramos-Polo, Josep Francesch Manzano, Míriam Corbella Santano et autres

The soluble transferrin receptor (sTfR) is a marker of tissue iron status, which could indicate an increased iron demand at the tissue level. The impact of sTfR levels on functional capacity and quality of life (QoL) in non-anemic heart failure (HF) patients …

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