Javad Hamidi Esfahani

Magnetic Susceptibility Separation Reveals Longitudinal Lesion Changes in Multiple Sclerosis

Ziyan Zhu, Javad Hamidi Esfahani, Nashwan Naji, Peter Seres et autres

Susceptibility separation may distinguish iron and myelin in multiple sclerosis (MS) lesions, but little work has been done on longitudinal changes. Twenty MS subjects were followed for 14 months to investigate para and diamagnetic changes independently using susceptibility separation in comparison to …

MR Susceptibility Separation for Quantifying Lesion Paramagnetic and Diamagnetic Evolution in Relapsing–Remitting Multiple Sclerosis

Ziyan Zhu, Nashwan Naji, Javad Hamidi Esfahani, Jeff Snyder et autres

Background Multiple sclerosis (MS) lesion evolution may involve changes in diamagnetic myelin and paramagnetic iron. Conventional quantitative susceptibility mapping (QSM) can provide net susceptibility distribution, but not the discrete paramagnetic and diamagnetic components. Purpose To apply susceptibility separation (χ separation) to follow …

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Repeatability of Susceptibility Separation in Brain

Javad Hamidi Esfahani, Nashwan Naji, Peter Seres, Christian Beaulieu et autres

Susceptibility separation enables a voxel-wise decomposition into paramagnetic and diamagnetic components. The repeatability of the method is examined in four structures of deep gray matter and three of white matter using scan rescan data of 22 subjects. The paramagnetic susceptibility separation is …