Perrine Verdys

Myosins 1e/f at the podosome base regulate podosome dynamics and promote macrophage migration

Pasquale Cervero, Sarah R. Barger, Perrine Verdys, Robert Herzog et autres

Cells of the monocyte lineage form specialized membrane-associated, actin-rich structures, called podosomes. Podosomes play important roles in cell adhesion and migration as well as the proteolytic degradation of the extracellular matrix. While podosomes are always closely associated with the plasma membrane, the …

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Moesin controls cell–cell fusion and osteoclast function

Ophélie Dufrançais, Marianna Plozza, Marie Juzans, Arnaud Métais et autres

Cell-cell fusion is an evolutionarily conserved process that is essential for many functions, including the formation of bone-resorbing multinucleated osteoclasts. Osteoclast multinucleation involves dynamic interactions between the actin cytoskeleton and the plasma membrane that are still poorly characterized. We found that moesin, …

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Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration

Pasquale Cervero, Sarah R. Barger, Perrine Verdys, Robert Herzog et autres

Cells of the monocyte lineage form specialized membrane-associated, actin-rich structures, called podosomes. Podosomes play important roles in cell adhesion and migration as well as the proteolytic degradation of the extracellular matrix. While podosomes are always closely associated with the plasma membrane, the …

de, us, fr (code pays fourni par la source)

Ezrin, radixin, and moesin are dispensable for macrophage migration and cellular cortex mechanics

Perrine Verdys, Javier Rey-Barroso, Adeline Girel, Joseph Vermeil et autres

The cellular cortex provides crucial mechanical support and plays critical roles during cell division and migration. The proteins of the ERM family, comprised of ezrin, radixin, and moesin, are central to these processes by linking the plasma membrane to the actin cytoskeleton. …

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Moesin controls cell-cell fusion and osteoclast function

Ophélie Dufrançais, Perrine Verdys, Marianna Plozza, Arnaud Métais et autres

ABSTRACT Cell-cell fusion is an evolutionarily conserved process that is essential for many functions, including fertilisation and the formation of placenta, muscle and osteoclasts, multinucleated cells that are unique in their ability to resorb bone. The mechanisms of osteoclast multinucleation involve dynamic …

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Author Reply to Peer Reviews of The membrane-actin linkers ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics.

Perrine Verdys, Javier Rey Barroso, Joseph Vermeil, Martin Bergert et autres

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The membrane-actin linkers ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics

Perrine Verdys, Javier Rey Barroso, Joseph Vermeil, Martin Bergert et autres

Abstract The cellular actin cortex provides crucial mechanical support and plays critical roles in numerous functions, including cell division and migration. The proteins of the ERM family, ezrin, radixin, and moesin, are central to these processes by linking the plasma membrane to …

fr, ca, de (code pays fourni par la source)

Etude du rôle des protéines Ezrine, Radixine et Moésine (ERM) dans la migration des macrophages

Perrine Verdys

Le cortex cellulaire sert de support mécanique et joue un rôle clé dans une diversité de structures cellulaires impliquées dans de nombreuses fonctions, parmi lesquelles la division et la migration cellulaire. Les trois protéines de la famille ERM : l'ezrine, la radixine …

Roles of Ezrin, Radixin and Moesin (ERM) in macrophage migration

Perrine Verdys

Etude du rôle des protéines Ezrine, Radixine et Moésine (ERM) dans la migration des macrophages Le cortex cellulaire sert de support mécanique et joue un rôle clé dans une diversité de structures cellulaires impliquées dans de nombreuses fonctions, parmi lesquelles la division …

fr (code pays fourni par la source)