Sara Mirzazadeh

Metabolic switch: lymphocytes and the onset of T-cell-mediated autoimmunity

Andisheh Mosaffa Jahromi, Fatemeh Mirzaei, Sara Mirzazadeh, Seppo Meri et autres

T cell-mediated autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (RA), and type 1 diabetes (T1D), are being increasingly recognized as disorders driven not only by immune dysregulation but also by profound metabolic reprogramming in lymphocytes. Emerging evidence from the field of …

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Alterations in metabolic pathways: a bridge between aging and weaker innate immune response

Zahra Saleh, Sara Mirzazadeh, Fatemeh Mirzaei, Kamran Heidarnejad et autres

Aging is a time-dependent progressive physiological process, which results in impaired immune system function. Age-related changes in immune function increase the susceptibility to many diseases such as infections, autoimmune diseases, and cancer. Different metabolic pathways including glycolysis, tricarboxylic acid cycle, amino acid …

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Activating KIR/HLA-I combinations as a risk factor of adult B-ALL

Hossein Halimi, Sara Mirzazadeh, Kurosh Kalantar, Maryam Hajimaghsoodi et autres

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Association study between killer immunoglobulin-like receptor polymorphisms and susceptibility to COVID-19 disease: a systematic review and meta-analysis

Saeed Hosseini Teshnizi, Sara Mirzazadeh, Niloofar Mashhadi, Seppo Meri et autres

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Association of killer cell immunoglobulin-like receptors and their cognate HLA class I ligands with susceptibility to acute myeloid leukemia in Iranian patients

Sara Mirzazadeh, Peyman Bemani, Hossein Halimi, Mohammad Nabi Sanaee et autres

Abstract Acute myeloid leukemia (AML) is one of the most prevalent leukemia in adults. Among the various NK receptors, killer immunoglobulin-like receptors (KIRs) carry out indispensable roles in NK cell development and function through engaging with class I human leukocyte antigens (HLA-I) …

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