Accès ouvert
2025
article
OpenAlex
N. Pell, Pauline Bernard, Séverine Courrech, Lukáš Opálka et autres
Congenital ichthyoses, now renamed Epidermal Differentiation Disorders (syndromic, sEDD or nonsyndromic, nEDD) are rare, disabling conditions caused by sequence variations in epidermal barrier genes. However, 5–10% of variants, called "Variants of Uncertain Significance" (VUS), remain uncharacterized and their pathogenicity not demonstrated. We …
fr, cz, es
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Accès ouvert
2025
article
OpenAlex
Aïna Millán‐Sánchez, Noèlia Loza-Rodríguez
Ceramides play crucial roles in membrane function and structure. Ceramide EOS (CerEOS) is essential in forming the skin intercellular lipid lamellae and its absence causes an impaired skin barrier, leading to skin disorders such as Autosomal Recessive Congenital Ichthyoses. Despite its biological …
es
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Accès ouvert
2025
article
OpenAlex
Noèlia Loza-Rodríguez, Aïna Millán‐Sánchez, Aleix Benítez, Ramón Pons et autres
A graphical representation of the development process of a lipidic hydrogel loaded with an anti-HIV peptide for pre-exposure prophylaxis: characterization, ex vivo mucosa permeation, and efficacy testing in vaginal mucosa.
es
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Accès ouvert
2024
article
OpenAlex
Noèlia Loza-Rodríguez, Aïna Millán‐Sánchez, Mireia Mallandrich, Ana Cristina Calpena et autres
This study explores the incorporation of 10% 3-O-ethyl L-ascorbic acid (ETVC), a derivative of vitamin C, into two lipid gel systems: a hydrogel (HG) consisting exclusively of lipids and water and a bigel (BG) combining the hydrogel with an oleogel made from …
es
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Accès ouvert
2023
article
OpenAlex
Noèlia Loza-Rodríguez, Aïna Millán‐Sánchez, Olga López Serrano
Ascorbic acid (AA) has many health benefits, including immune and cardiovascular deficiency protection, prenatal problems, and skin diseases. Unfortunately, AA is easily oxidized and has limited bioavailability. Thus, the development of formulations that stabilize and enhance the efficacy of AA is a …
es
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Accès ouvert
2023
article
OpenAlex
Noèlia Loza-Rodríguez, Aïna Millán‐Sánchez, Olga López Serrano
The development of biocompatible delivery systems is a necessity for medical and topical applications. Herein, the development of a new bigel for topical application is described. It is composed of 40% colloidal lipid hydrogel and 60% olive oil and beeswax oleogel. Its …
es
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2019
article
OpenAlex
Anna Salazar‐Degracia, Paula Granado‐Martínez, Aïna Millán‐Sánchez, Jun Tang et autres
Identification of to what extent tumor burden influences muscle mass independently of specific treatments for cancer-cachexia remains to be elucidated. We hypothesized that reduced tumor burden by selective treatment of tumor with immunomodulators may exert beneficial effects on muscle wasting and function …
es
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