Marina-Daniela Dimulescu

Association of germline ABCB1 and ERCC1 polymorphisms with CDK4/6 inhibitor-induced neutropenia in patients with breast cancer: a systematic review and meta-analysis

Marina-Daniela Dimulescu, Cristian Virgil Lungulescu, Anca‐Lelia Riza, Ioana Streata et autres

Background CDK4/6 inhibitors are standard-of-care for HR+/HER2− advanced breast cancer, but grade 3/4 neutropenia occurs in up to 60% of patients. Germline polymorphisms in ABCB1 , encoding the P-glycoprotein efflux transporter, have been investigated as predictors of CDK4/6 inhibitor–induced neutropenia, with conflicting …

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Digital Training and Vaccination Safety: Knowledge Gains, Persistent Misconceptions and Conditional Willingness Among Romanian Community Pharmacists

Adina Turcu-Ştiolică, Marius Călin Cherecheș, Marina-Daniela Dimulescu, Mihaela-Simona Naidin

ro (code pays fourni par la source)

Digital Training and Vaccination Safety: Knowledge Gains, Persistent Misconceptions and Conditional Willingness Among Romanian Community Pharmacists

Adina Turcu-Ştiolică, Marius Călin Cherecheș, Marina-Daniela Dimulescu, Mihaela-Simona Naidin

ro (code pays fourni par la source)

Association of germline ABCB1 and ERCC1 polymorphisms with CDK4/6 inhibitor-induced neutropenia in patients with breast cancer: a systematic review and meta-analysis.

Marina-Daniela Dimulescu, Cristian Virgil Lungulescu, Anca‐Lelia Riza, Ioana Streata et autres

Background: , encoding the P-glycoprotein efflux transporter, have been investigated as predictors of CDK4/6 inhibitor-induced neutropenia, with conflicting results across populations. No meta-analysis has previously pooled these findings. Methods: rs3212986. Odds ratios were pooled using Mantel-Haenszel weighting with random-effects (rs1128503, rs11615) or …

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PCR267 What Affects Quality of Life Most in Oral Cancer Therapy? A Pilot Study of Adherence and Side Effects

Marina-Daniela Dimulescu, Cristian Virgil Lungulescu, Mihaela-Simona Naidin, Andreea-Maria Gane et autres

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Changes in Quality of Life Among Glaucoma Patients Following Six Months of Niacinamide Supplementation

Maria Cristina Marinescu, Anne Marie Firan, Georgică Târtea, Mihaela-Simona Naidin et autres

Background/Objectives: Glaucoma is the primary cause of irreversible blindness worldwide, with enormous impact on quality of life and activities of daily living. Since one pathogenic mechanism of glaucoma is mitochondrial dysfunction at the retinal ganglion cell level, niacin has been proposed as …

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Pharmacists’ perceptions of the new pharmaceutical vaccination service in Romania: a comprehensive first two-years evaluation

Corneliu-Florin Buicu, Mihaela-Simona Naidin, Marius Călin Cherecheș, Marina-Daniela Dimulescu et autres

Introduction Pharmacy-based vaccination services are now available in 56 countries, including Romania, that started administering the flu-vaccines in the community pharmacies from 2022. Assessing how pharmacists managed this new pharmaceutical service in Romania is the subject of this study. Methods A cross-sectional …

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Real-World Efficacy and Adherence to Palbociclib in HR-Positive, HER2-Negative Advanced Breast Cancer: Insights from a Romanian Cohort

Cristian Virgil Lungulescu, Georgiana-Cristiana Camen, Mihaela-Simona Naidin, Tradian-Ciprian Berisha et autres

Background/Objectives: The first reimbursed prescription for palbociclib (Palbo) in breast cancer patients in Romania was issued in July 2018. The objective of this study is to assess the efficacy, safety, and adherence to Palbo in combination with aromatase inhibitor (AI) or fulvestrant …

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PCR54 Monitoring Health-Related Quality of Life Following Dietary Supplementation With Folic Acid, Vitamin B12, and Vitamin D3 in Patients Diagnosed With Parkinson Disease in Romania

Adina Turcu-Ştiolică, MS Naidin, Marina-Daniela Dimulescu, M. Turcu-Stiolica et autres

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PCR165 Translation and Cultural Adaptation of the Essential Tremor Embarrassment Assessment (ETEA) Questionnaire to the Romanian Population

M.S. Subtirelu, M. Turcu-Stiolica, Marina-Daniela Dimulescu, Adina Turcu-Ştiolică

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Diagnosis and risk factors for intracranial aneurysms in autosomal polycystic kidney disease: a cross-sectional study from the Genkyst cohort

Siriane Lefèvre, Marie‐Pierre Audrézet, Jean‐Michel Halimi, Hélène Longuet et autres

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is associated with an increased risk for developing intracranial aneurysms (IAs). We aimed to evaluate the frequency of diagnosis of IAs in the cross-sectional, population-based, Genkyst cohort, to describe ADPKD-associated IAs and to analyse the …

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