Rafael Simó

Recent and long-term glycation markers and asymptomatic cerebral microangiopathy in adults without diabetes: the ILERVAS study

Francesc Purroy, Gerard Mauri-Capdevila, Marcelino Bermúdez-López, José Manuel Valdivielso et autres

Cerebral microangiopathy encompasses a spectrum of pathological alterations affecting the brain microvasculature. Elevated glycated haemoglobin (HbA1c), a marker of recent glycemic exposure, has been associated with a greater burden of subclinical atherosclerosis in the carotid and femoral territories of non-diabetic individuals. In …

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Neuroprotection in Early Diabetic Retinal Disease Using Eyedrop Delivery

Hugo Ramos, Olga Simó‐Servat, Cristina Hernández, Rafael Simó

Diabetic retinal disease (DRD) has classically been defined as a microvascular complication of diabetes; however, the recent evidence highlighted the key role of neuronal degeneration during the earliest stages of its pathogenesis. Therefore, neuroprotection has emerged as a promising therapeutic strategy to …

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Obstructive sleep apnea risk and its association with diabetic foot ulcer in patients with type 2 diabetes

Raquel Ruano, María Teresa Charles, Josep León-Mengíbar, Ferran Barbé et autres

Background: Obstructive sleep apnea (OSA) is common in type 2 diabetes (T2D) and may contribute to its chronic complications. Whether STOP-Bang-defined OSA risk is associated with diabetic foot ulcer (DFU) severity and outcome remains unclear. We compared STOP-Bang score between T2D patients …

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Subclinical overhydration predicts lower time in range and greater glycemic variability in type 2 diabetes on hemodialysis

Pedro Gil-Millan, Ascension Lupianez, Sònia Caparrós, Alicia Ribas et autres

Overhydration may influence glycemic control in patients with type 2 diabetes (T2D) undergoing hemodialysis (HD). We investigated whether the extracellular-to-total body water ratio (ECW/TBW), a marker of fluid overload, is associated with Time in Range (TIR) and glucose variability (GV) in this …

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O-023. IMPACTO DE LA PREDIABETES SOBRE LA ENFERMEDAD RENAL: ESTUDIO BASAL Y EVOLUCIÓN A 4 AÑOS EN LA COHORTE ILERVAS

Albert Lecube Torelló, Aitziber Izarra, Marcelino Bermúdez, Pedro Gil et autres

P-126. IMPACTO DE LA ADIPOSIDAD VISCERAL Y LA HIPERHIDRATACIÓN SUBCLÍNICA EN EL TIEMPO EN RANGO EN PACIENTES CON DIABETES TIPO 2 EN HEMODIÁLISIS

Pedro Gil-Millan, Ascension Lupianez, Sònia Caparrós, Ángel Ortiz-Zuñiga et autres

P-125. VARIABILIDAD GLUCÉMICA EN PACIENTES CON DIABETES TIPO 2 EN HEMODIÁLISIS: VALOR PREDICTIVO DEL ÍNDICE CINTURA-ALTURA

Pedro Gil-Millan, Ascension Lupianez, Sònia Caparrós, Ángel Ortiz-Zuñiga et autres

Impact of visceral adiposity on glycemic variability in patients with insulin-treated type 2 diabetes undergoing hemodialysis

Pedro Gil-Millan, Ascension Lupianez, Sònia Caparrós, Alicia Ribas et autres

BACKGROUND Glycemic variability (GV) is increasingly recognized as a major metabolic risk in patients with type 2 diabetes (T2D) undergoing hemodialysis (HD); however, key contributors remain unclear. AIM To identify clinical predictors of GV – measured by differences in time in range …

Association between socioeconomic status and diabetic retinopathy in individuals with type 1 diabetes: a systematic review and meta-analysis

Fernando Sebastián‐Valles, Sergio Núñez de Arenas‐Arroyo, Olga Simó-Servat, Rafael Simó et autres

BACKGROUND: Despite improvements in screening and diabetes management, diabetic retinopathy (DR) remains a leading cause of vision loss in individuals with type 1 diabetes (T1D). Although clinical risk factors for DR are well established, the impact of socioeconomic status (SES) on DR …

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Diabetes-linked metabolic dysfunction relates with distinct tau phosphorylation patterns, neuroinflammation and cognitive impairment in mouse models of Alzheimer’s disease

María Vargas-Soria, Miriam Corraliza-Gómez, Carmen Infante‐Garcia, Alan W. Stitt et autres

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Sex-specific metabolic effects of Treg expansion in db/db mice

María Jose Canz, Elisabet Torras-Peyrotón, Anna Álvarez-Guaita, Lorena Ramos-Pérez et autres

Introduction Type 2 diabetes mellitus (T2D) is characterized by chronic, low-grade inflammation and immune dysregulation, contributing to insulin resistance and metabolic complications. Regulatory T cells (Tregs) are key modulators of immune homeostasis, and their therapeutic expansion has shown promise in limiting inflammation. …

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Impact of the new EASO obesity definition on the detection of atheromatosis in subjects with low-to-moderate cardiovascular risk

José León, Marcelino Bermúdez-López, José Manuel Valdivielso, Reinald Pamplona et autres

Background Traditional body mass index (BMI) does not adequately reflect adipose tissue distribution and associated cardiovascular (CV) risk. To improve risk stratification, the European Association for the Study of Obesity (EASO) proposes to extend the diagnosis of obesity to include individuals with …

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