Accès ouvert
2025
article
OpenAlex
Michael J. Haller, Lauren G. Kanapka, Roshanak Monzavi, Thomas J. Mouse et autres
OBJECTIVE: To evaluate inhaled technosphere insulin (TI) in children with diabetes. RESEARCH DESIGN AND METHODS: A total of 230 youth 4-17 years old with type 1 (98%) or type 2 (2%) diabetes treated with multiple daily injections of insulin were randomly assigned …
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Accès ouvert
2025
article
OpenAlex
Akshay S. Desai, Adam D. Karns, Jolita Badarienė, Ahmad Aswad et autres
Importance: In prior monotherapy studies of patients with hypertension, single subcutaneous doses of zilebesiran, an investigational RNA interference therapeutic, reduced serum angiotensinogen levels and systolic blood pressure (SBP) at 3 and 6 months. Objective: To evaluate the efficacy and safety of zilebesiran …
us, lt, gb
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Accès ouvert
2022
article
OpenAlex
Nicolas M. Van Mieghem, G. Michael Deeb, Lars Søndergaard, Eberhard Grube et autres
Importance: In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling stroke at 2 years. Comparisons of longer-term clinical and hemodynamic outcomes …
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Accès ouvert
2021
article
OpenAlex
Altaf Panjwani, Mitesh Patel, Colten Youngblood, Alessandro Lione et autres
In any cardiac patient, efforts should be made to avoid volume overload, especially around the time of surgery. Continuous retrograde Del Nido cardioplegia, a common practice for maintaining cardiac arrest during a procedure when a patient has patent circulation, has the unintended …
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