The immune microenvironment in hormone receptor-positive breast cancer before and after preoperative chemotherapy
Y. Wu, R. Wesolowski, W. Osmani, Hans-Waldemar Brauer et autres
Purpose: Hormone receptor-positive/HER2-negative (HR+/HER2_) breast cancer is associated with low levels of stromal tumor-infiltrating lymphocytes (sTIL) and PD-L1, and demonstrates poor responses to checkpoint inhibitor therapy. Evaluating the effect of standard chemotherapy on the immune microenvironment may suggest new opportunities for immunotherapy-based …
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