Michael Fisch

Associations between self-efficacy and symptom burden in young women with breast cancer initiating endocrine therapy (ET) on SWOG S2010.

N. Lynn Henry, Amy Kristine Darke, Joseph M. Unger, Anne F. Schott et autres

521 Background: Self-efficacy (SE) is the belief in one's ability to succeed in specific situations or accomplish a task, influencing motivation, behavior, and resilience. Both symptom (sx) burden at the time of ET initiation and lower SE for sx management are associated …

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Immune checkpoint inhibitor (ICI) toxicity in a large prospective cohort of patients with solid tumors: The I-CHECKIT study (SWOG S2013).

Krishna S. Gunturu, Joseph M. Unger, Dawn L. Hershman, Amy Kristine Darke et autres

2640 Background: Based on clinical trials, the expected rate of ≥ grade 3 iRAEs is ~15% for single agent ICIs and ~30-50% for ipilumimab (ipi) plus nivolumab (nivo). Predictors of irAEs remain poorly defined, limiting clinicians’ ability to anticipate and manage irAEs …

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A risk prediction model for severe, life-threatening, and fatal treatment-related toxicity.

Joseph M. Unger, N. Lynn Henry, Michael Fisch, Dawn L. Hershman

12143 Background: Adverse events are major contributors to morbidity and mortality in patients receiving systemic cancer therapy. Accurate prediction of high-grade toxicity could inform risk-adapted treatment strategies. Methods: This cohort study included data from 18 SWOG adult phase 2 and 3 treatment …

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Vitamin D insufficiency and risk of taxane-induced peripheral neuropathy: Results from SWOG S1714.

Nam Nguyen-Hoang, Joseph M. Unger, Amy Kristine Darke, Michael Fisch et autres

12012 Background: Taxane-induced peripheral neuropathy (TIPN) affects up to 70% of patients treated with taxanes and can lead to functional impairment, reduced quality of life, and treatment disruption. There are no proven TIPN preventive strategies. Vitamin D insufficiency is a modifiable factor …

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The association of baseline fatigue and severe cancer treatment toxicity by comorbid conditions: A pooled analysis.

Michael M. Caplan, Joseph M. Unger, Cathee Till, Michael Fisch et autres

11036 Background: Fatigue is commonly reported by patients with cancer. Patients who report fatigue are at greater risk of severe adverse events during treatment. However, it is unknown whether the relationship between baseline fatigue and toxicity risk persists after accounting for comorbid …

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Post-treatment recovery patterns among patients with early-stage cancer who develop taxane-induced peripheral neuropathy (TIPN): SWOG S1714 (NCT03939481).

Meghna S. Trivedi, Joseph M. Unger, Daniel Louis Hertz, Cathee Till et autres

12117 Background: The primary analysis of S1714 developed and validated a TIPN risk prediction model including 5 clinical risk factors. Recovery patterns of TIPN are not well described. Although some symptoms may improve with time, other symptoms may persist or worsen as …

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Engendering Reproductive Health Within Oncologic Survivorship Trial, ECOG-ACRIN E1Q11

Ashlesha Patel, Ju‐Whei Lee, Howard A. Zaren, Erika K. Radeke et autres

PURPOSE For the 10% of women diagnosed with cancer within reproductive age, reproductive health is a critical component of oncologic survivorship. Variable attention to guidelines pertaining to oncocontraception and oncofertility results in cancer care discordant with a patient's reproductive health goals, negatively …

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Risk Prediction Model for Taxane-Induced Peripheral Neuropathy in Early-Stage Cancer

Meghna S. Trivedi, Joseph M. Unger, N. Lynn Henry, Amy K. Darke et autres

Importance: Taxane-induced peripheral neuropathy (TIPN) affects quality of life and ability to complete cancer treatment and has limited effective interventions for prevention and treatment. Objective: To develop and validate a TIPN risk prediction model. Design, Setting, and Participants: SWOG S1714 was a …

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Baseline Fatigue and Severe Toxic Effects in Patients With Cancer Receiving Systemic Therapy

Joseph M. Unger, Michael Fisch, Salene M. W. Jones, N. Lynn Henry et autres

Importance: Fatigue is a common symptom reported by patients with cancer, yet its role as a predictor of treatment-related toxic effects has not been well characterized. Understanding whether fatigue measured at treatment initiation may be associated with subsequent toxic effects could help …

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17 Quellen zum zwanzigsten Jahrhundert (von 1975 bis 1984)

Michael Fisch

1478 Quellen zum zwanzigsten Jahrhundert (von 1985 bis 1994)

Michael Fisch

47910 Quellen zum einundzwanzigsten Jahrhundert (von 2000 bis 2004)

Michael Fisch