Amanda Ho

Mechanisms of Anxiety Reduction During Adult Coloring: Mindfulness, Flow, Enjoyment, and Distraction

Sharon M. Flicker, Flavia Sancier‐Barbosa, An‐Na Tang, Amanda Ho et autres

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Commensal Bacteria Modulate the Immune Response to Radiation Therapy (RT) in a Murine Oral Cavity Model

Elvin Canseco, S. Stevens, J. Viramontes, Ignacio Vásquez et autres

MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis

Y.K. Zheng, Fei Han, Zhengyu Wu, B. Wang et autres

Mucosal-associated invariant T (MAIT) cells are antimicrobial T cells abundant in the gut, but mechanisms for their migration into tissues during inflammation are poorly understood. Here, we used acute pediatric appendicitis (APA), a model of acute intestinal inflammation, to examine these migration …

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Role of MAIT cells in gastrointestinal tract bacterial infections in humans: More than a gut feeling

Yi‐Chao Zheng, Fei Han, Amanda Ho, Yiting Xue et autres

)-like metabolite antigens derived from microbial riboflavin biosynthetic pathway. Presentation of this unique class of small molecule metabolite antigens is mediated by the highly evolutionarily conserved major histocompatibility complex class I-related protein. In humans, MAIT cells are widely found along the upper …

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IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection

Fei Han, Muhammad Yaaseen Gulam, Yi‐Chao Zheng, Nurul Syuhada Zulhaimi et autres

MAIT cells are persistently depleted and functionally exhausted in HIV-1-infected patients despite long-term combination antiretroviral therapy (cART). IL-7 treatment supports MAIT cell reconstitution in vivo HIV-1-infected individuals and rescues their functionality in vitro. Single-nucleotide polymorphisms (SNPs) of the IL-7RA gene modulate the …

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Phosphorus metabolism in the brain of cognitively normal midlife individuals at risk for Alzheimer's disease

Prodromos Parasoglou, Ricardo S. Osorio, Oleksandr Khegai, Zanetta Kovbasyuk et autres

Background Neurometabolic abnormalities and amyloid-beta plaque deposition are important early pathophysiologic changes in Alzheimer's disease (AD). This study investigated the relationship between high-energy phosphorus-containing metabolites, glucose uptake, and amyloid plaque using phosphorus magnetic resonance spectroscopy ( 31 P-MRS) and positron emission tomography …

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MAIT Cell Loss and Reconstitution in HIV-1 Disease

Fei Han, Yi‐Chao Zheng, Amanda Ho, Shaohua Ma et autres

Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that recognize microbial riboflavin-related metabolites presented by the evolutionarily conserved MHC class I-related (MR1) molecule. MAIT cells are abundant in circulation and mucosal tissues and are poised to mount rapid effector responses …

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Electrophysiological evidence for the integral nature of tone in Mandarin spoken word recognition

Amanda Ho, Rober Boshra, Daniel Schmidtke, Gaisha Oralova et autres

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Reducing the ecological footprint of Pie R Squared : the introduction of cheese-less pizza

Michael J. Chen, Adya Djoko, Amanda Ho, Sharon Kaler et autres

In order to alleviate the ecological footprint of Pie R Squared, the implementation of a cheese-less pizza into the current menu was pursued as a potential solution. Through conducting a pizza sampling survey, statistically significant data prove this strategy to be a …

Role Models and the Psychological Characteristics That Buffer Low-Socioeconomic-Status Youth From Cardiovascular Risk

Edith Chen, William K. Lee, Lisa Cavey, Amanda Ho

Little is understood about why some youth from low-socioeconomic-status (SES) environments exhibit good health despite adversity. This study tested whether role models and "shift-and-persist" approaches (reframing stressors more benignly while persisting with future optimism) protect low-SES youth from cardiovascular risk. A total …

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Healthy Hospital Food Environment: the PCMH Story.

Preston Comeaux, Russ Currie, Jeff Dial, Scottie Gaskins et autres

This paper describes Pitt Memorial Hospital's response to the call to become a healthy worksite. It describes the hospital's effots to partner in the North Carolina Plan to Prevent Overweight and Obesity and Related Chronic Conditions. Way to define healthy eating healthy …