Halima Alem

Size-Dependent Thermoresponsive Magnetic Core/Shell Nanoparticles for Controlled Doxorubicin Release and Hyperthermia-Assisted Cancer Therapy

Halima Alem, Dounia Louaguef, C. Godier, Melanie Emo et autres

Thermoresponsive magnetic core/shell nanoparticles were developed for controlled drug delivery in cancer therapy. Polyhedral Zn₀.₄Fe₂.₆O₄@MnFe₂O₄ nanoparticles with two core sizes (22 and 50 nm) were synthesized and coated with a thermosensitive copolymer shell composed of 2-(2-methoxy)ethyl methacrylate and oligo(ethylene glycol) methacrylate units, …

fr, my (code pays fourni par la source)

Cartilage tissue-engineered products based on mesenchymal stromal cells to build a joint-on-chip

Nicolas Potier, Christel Henrionnet, Laurent Grossin, Didier Mainard et autres

International audience

Aqueous synthesis of biocompatible and photoluminescent Mn-, Gd- or Fe-doped Ag-In-Zn-S quantum dots for cell imaging

Perizat Galiyeva, Henri-Pierre Lasalle, H. Rinnert, Lavinia Balan et autres

We report a facile three-step aqueous synthesis of highly luminescent Ag-In-Zn-S (AIZS) quantum dots (QDs) doped with Mn, Gd, or Fe ions using glutathione (GSH) as biocompatible stabilizer. Conducted entirely in aqueous media at mild temperatures (100 °C) under ambient conditions, this …

fr, kz (code pays fourni par la source)

Development of a millifluidic system incorporating cartilage tissue-engineered products based on mesenchymal stromal cells

Nicolas Potier, Christel Henrionnet, Laurent Grossin, Didier Mainard et autres

International audience

Reflector-Free, Highly Confined Love-Like SAWs Enabled by a Phononic Metasurface for Real-Time Monitoring of Cell Dynamics

Jessica Monaldi, F. Kosior, Julio A. Iglesias Martínez, Laurent Badie et autres

Surface acoustic wave (SAW) devices are widely used in sensing and biosensing but generally suffer from strong attenuation in liquid environments. Conventional approaches rely on reflectors to reduce these losses, yet these components remain difficult to optimize: limited device miniaturization, and increase …

Reflector-Free, Highly Confined Love-Like SAWs Enabled by a Phononic Metasurface for Real-Time Monitoring of Cell Dynamics

Jessica Monaldi, F. Kosior, Julio A. Iglesias Martínez, Laurent Badie et autres

Surface acoustic wave (SAW) devices are widely used in sensing and biosensing but generally suffer from strong attenuation in liquid environments. Conventional approaches rely on reflectors to reduce these losses, yet these components remain difficult to optimize: limited device miniaturization, and increase …

fr (code pays fourni par la source)

A combinative approach for the selective cellularization of human capillary-sized microchannels

Daniele Pedroni, Caroline Gaucher, Laurent Badie, Halima Alem

Abstract The controlled cellularization of enclosed microchannels with true capillary dimensions remains a major technical limitation in in vitro vascular models. While endothelial cell seeding is routinely achieved in microchannels with dimensions above several tens of micrometers, reliable and spatially selective endothelialization …

fr (code pays fourni par la source)

Tuning photoactivity and photoprotection of TiO 2 via TiO 2 /CeO 2 heterostructure composite engineering

Michał Gackowski, Dariusz T. Młynarczyk, Halima Alem, Joanna Budna-Tukan et autres

heterostructuring is an effective, safe-by-design strategy for developing photoprotective excipients that stabilize photosensitive drugs in topical formulations.

pl, fr (code pays fourni par la source)

Strategies for modelling the intestinal mucus interface: focus on drug transport and host-microbiota interactions

Halima Alem, Aixa Aguilera-Garrido

High performance hydrogen photoproduction using a Co-doped CuBDC metal organic framework

Sher Mohd, Lavinia Balan, Thomas Gries, Halima Alem et autres

Co-doped CuBDC prepared using the 4-FBA defective linker exhibits high photocatalytic activity for hydrogen production under visible light irradiation.

fr (code pays fourni par la source)

Improving magnetic properties of Mn- and Zn-doped core–shell iron oxide nanoparticles by tuning their size

Dounia Louaguef, Ghouti Medjahdi, Sébastien Diliberto, K. Seemann et autres

Superparamagnetic iron oxide nanoparticles (SPIONs) offer promising applications in nanomedicine due to their appealing properties. Their magnetic and magnetic hyperthermia properties are considered as relevant tools for low invasive cancer therapeutic applications. In this work, we report on the synthesis of polyhedral …

fr (code pays fourni par la source)

Micropatterning of Glass Substrates Using Electron‐Beam Lithography for Morphological Analysis of Human Umbilical Vein Endothelial Cells

Daniele Pedroni, Caroline Gaucher, Demba Ba, Laurent Badie et autres

This study presents a micropatterning technique for glass substrates aimed at investigating the morphological adaptations of human umbilical vein endothelial cells (HUVECs). This method employs electron‐beam lithography technology to produce sacrificial structures on glass prior to gas‐phase deposition of polyethylene glycol‐bearing silanes. …

fr (code pays fourni par la source)