Ruoran Wang

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jimin Xu

As an important anticoagulant molecule, antithrombin III (ATIII) has been confirmed to inhibit inflammation and to alleviate renal ischemia-reperfusion injury. The present study aimed to explore the relationship between serum ATIII level and acute kidney injury (AKI) in patients with traumatic brain …

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The prognostic nomogram for predicting mortality of elderly acute pancreatitis patients: A retrospective cohort study of the MIMIC-III database

Lijie Wang, Yusi Hua, Ruoran Wang, Xiaofeng Ou

With the aging of the world population, the number of elderly patients with acute pancreatitis (AP) is increasing. The morbidity and mortality are significantly increased in elderly AP patients. This study aims to establish a model to predict the mortality of elderly …

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A machine learning predictive model for acute kidney injury among aneurysmal subarachnoid hemorrhage patients

Ruoran Wang, Yunhui Zeng, Linrui Cai, Min He et autres

BACKGROUND: Acute kidney injury (AKI) has been confirmed to be related to the prognosis of aSAH patients. Evaluating the risk of AKI in the early stage is important to avoid the unfavorable outcome of aSAH patients. However, no study has explored the …

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Author Correction: Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus

Qintao Wang, Honghao Zhu, Xiangwei Sun, Changming Zhang et autres

In the version of this article initially published, due to figure preparation mistakes, the image shown in Fig. 2g for IL-23 was a duplicate of the GM-CSF image below; in Extended Data Fig. 2c, the C1 plot for IFN-α was a duplicate …

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Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus

Qintao Wang, Honghao Zhu, Xiangwei Sun, Changming Zhang et autres

. Here we report on five patients with SLE carrying recessive mutations in phospholipase D family member 4 (PLD4). Deleterious variants in PLD4 resulted in impaired single-stranded nucleic acid exonuclease activity in in vitro and ex vivo assays. PLD4 loss-of-function mutations led …

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Reduced residual cholesterol is associated with increased mortality risk in patients with aneurysmal subarachnoid Hemorrhage: a retrospective study

Xihang Zeng, Ruoran Wang, Jianguo Xu

Background Residual cholesterol has been confirmed to be associated with the incidence of stroke and its prognosis. However, there is no study exploring the relationship between residual cholesterol and mortality in cases of aneurysmal subarachnoid hemorrhage (aSAH). Therefore, this study investigated the …

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The U-shaped association between initial serum phosphate level and mortality of traumatic brain injury patients

Ruoran Wang, Xin Yang, Jianguo Xu, Min He

Background Phosphate disorders, including hypophosphatemia and hyperphosphatemia, influence the prognosis of patients. We designed this study to explore the relationship between serum phosphate levels and mortality in traumatic brain injury (TBI) patients. Methods TBI patients from the Medical Information Mart for Intensive …

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Serum uric acid is associated with shunt dependent hydrocephalus of aneurysmal subarachnoid hemorrhage patients

Ruoran Wang, Jing Zhang, Jianguo Xu, Min He

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Association between initial serum cystatin C level and prognosis of aneurysmal subarachnoid hemorrhage

Ruoran Wang, Jing Zhang, Jianguo Xu, Min He

BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) patients usually suffer poor survival outcome and severe morbidity. Evaluating prognosis of aSAH patients in acute phase is essential for physicians to make suitable treatments strategies. This study was performed to explore the relation between initial serum …

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Association between serum phosphate level and mortality of patients with aneurysmal subarachnoid hemorrhage

Ruoran Wang, Jing Zhang, Jianguo Xu, Min He

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ABO blood type is not a risk factor of outcome in aneurysmal subarachnoid hemorrhage patients

Ruoran Wang, Jing Zhang, Jianguo Xu, Min He

BACKGROUND: The association between ABO blood types and outcome of aneurysm subarachnoid hemorrhage (aSAH) has not reached a conclusion. This study was performed to testify the difference of outcome between ABO blood types. METHODS: 663 aSAH patients hospitalized in the West China …

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Prognostic value of thrombocytopenia during hospitalizations in intracerebral hemorrhage patients

Hao Feng, Xiaoquan Luo, Anhui Fu, Ruoran Wang et autres

Background The thrombocytopenia influences prognoses of critically ill patients. There are few studies exploring the prognostic value of thrombocytopenia among ICH patients. We perform this study to explore the correlation between thrombocytopenia at different timepoints of hospitalizations and mortality of ICH. Methods …

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