Profil bibliographique

Ioanna Deni

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17Publications signalées

475Citations signalées

2Affiliations récentes

Institutions déclarées

Columbia University Irving Medical Center CNR de la Résistance aux Antibiotiques

Domaines associés

Malaria Research and ControlComputational Drug Discovery MethodsHIV/AIDS drug development and treatmentDrug Transport and Resistance MechanismsMosquito-borne diseases and control

Publications récentes

Accès ouvert 2025 articleOpenAlex

Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na + Pump ( Pf ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane et autres

3 citationsACS Infectious Diseases

Accès ouvert 2025 preprintOpenAlex

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na + pump ( Pf ATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane et autres

0 citationsbioRxiv (Cold Spring Harbor Laboratory)

Accès ouvert 2024 articleOpenAlex

Optimization of pyrazolopyridine 4-carboxamides with potent antimalarial activity for which resistance is associated with the P. falciparum transporter ABCI3

Petar P. S. Calic, Trent D. Ashton, Mahta Mansouri, Katie Loi et autres

12 citationsEuropean Journal of Medicinal Chemistry

Accès ouvert 2023 articleOpenAlex

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome

Ioanna Deni, Barbara H. Stokes, Kurt E. Ward, Kate J. Fairhurst et autres

29 citationsCell chemical biology

2022 articleOpenAlex

Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study.

Bridget E. Barber, Melissa Fernandez, Hardik B. Patel, Catalina Barceló et autres

30 citationsLSTM Online Archive (Liverpool School of Tropical Medicine)

Accès ouvert 2022 articleOpenAlex

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance

Jennifer L. Small-Saunders, Laura M. Hagenah, Kathryn J. Wicht, Satish K. Dhingra et autres

33 citationsPLoS Pathogens

Accès ouvert 2021 articleOpenAlex

Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome

Stanley C. Xie, Riley D. Metcalfe, Hirotake Mizutani, Tanya Puhalovich et autres

38 citationsProceedings of the National Academy of Sciences

Accès ouvert 2021 articleOpenAlex

Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

Barbara H. Stokes, Satish K. Dhingra, Kelly Rubiano, Sachel Mok et autres

180 citationseLife

Accès ouvert 2021 articleOpenAlex

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

James M. Murithi, Ioanna Deni, Charisse Flerida A. Pasaje, John Okombo et autres

31 citationsCell chemical biology

Accès ouvert 2021 peer-reviewOpenAlex

Author response: Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

Barbara H. Stokes, Satish K. Dhingra, Kelly Rubiano, Sachel Mok et autres

3 citations

Accès ouvert 2021 articleOpenAlex

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Michael Palmer, Xiaoyi Deng, Shawn Watts, Goran Krilov et autres

48 citationsJournal of Medicinal Chemistry

Accès ouvert 2021 reviewOpenAlex

Genomic and Genetic Approaches to Studying Antimalarial Drug Resistance and Plasmodium Biology

John Okombo, Mariko Kanai, Ioanna Deni, David A. Fidock

24 citationsTrends in Parasitology

Profil ORCID Notice OpenAlex

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