Jingjing Yu

Kitchen waste and dry-toilet exposure are likely associated with gut microbiota shifts, pathogen-associated taxa, and lipid metabolism-related functional potential in wild white-lipped deer in Xizang, China

Peng Luo, Xiao Zhang, Yu Zhao, Mingkun He et autres

Abstract Human disturbances significantly impact wildlife gut microbiota. Using metagenomic sequencing, we compared gut microbiota structure and lipid metabolism between two wild white-lipped deer populations on the Qinghai-Tibet Plateau: GBJD, where deer were observed consuming high-fat kitchen waste and licking feces-urine mixtures …

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Integrating ultrasound-CT-MR for preoperative multi-task prediction in ovarian cancer: achieving diagnostic parity with multidisciplinary team consensus

Jingjing Yu, Peijun Hu, Ruixia Dai, Xiaomin Liu et autres

BackgroundOvarian cancer, with its high mortality rate, requires precise preoperative integration of ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) for guide therapy, yet current clinical workflows rely on specialized multidisciplinary team (MDT) evaluations, a barrier in resource-limited settings. Current artificial …

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A Nomogram Predicting the Response to Tocilizumab in Treating Active, Moderate-To-Severe, Glucocorticoid-Resistant Thyroid Eye Disease: A Multicenter Retrospective Study

Jingjing Yu, Fanrui Meng, Zhipeng Cui, Zhiwei He et autres

Objective To evaluate the efficacy and safety of tocilizumab (TCZ) in treating active, moderate-to-severe, glucocorticoid-resistant thyroid eye disease (TED), and to develop a nomogram to predict the response to TCZ treatment.Methods This study involving 59 patients with active, moderate-to-severe, glucocorticoid-resistant TED from …

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An endoplasmic reticulum-targeting NIR fluorescent probe for viscosity imaging in vitro and vivo

Jian-Hua Tang, Jingjing Yu, Juntao Niu, Tong Han et autres

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Mdivi-1 alleviates aseptic craniofacial osteolysis via inhibition of PINK1/Parkin-dependent mitophagy

Xiaoyue Sun, Binqian Liu, Zhigui Li, Zijun Wang et autres

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[Expert consensus on the clinical application of endometrial ablation].

Hui Zhao, Linheng Li, Liming Chen, Qi Chen et autres

Evaluation of a novel bioceramic sealer NeoSEALER Flo on the activation and polarization of macrophage

Zijun Wang, Xiaoyue Sun, Zhuo Chen, Jingjing Yu et autres

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OCT-based retinal parameters and choroidal vascular indices predicting response to anti-TNF-α therapy in inflammatory bowel disease

Fenying Lu, Yue Du, Yijie Gu, Yujie Jiao et autres

• Novel OCT Biomarkers for IBD Monitoring Identifies retinal (RNFL, GCIPL, CMT) and choroidal (CVI, CC-VD, SF-CT) parameters as non-invasive predictors of IBD regression (AUCs 0.87-0.97). • High Predictive Accuracy for Biologic Therapy Response Demonstrates GCIPL and CC-VD as top biomarkers for …

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Amelioration of emotional processing deficits in individuals with high trait anxiety following high-intensity interval training

Chengcheng Li, Xiaoyi Che, Jingjing Yu, Fei Yan et autres

BACKGROUND: How does exercise alleviate anxiety related emotional processing deficits? This study measured the effect of both high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on motor cortical excitability corresponding to emotional perception in individuals with high trait anxiety. METHODS: Participants …

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Non-Alcoholic Fatty Liver Disease Aggravates Periodontitis In Mice

Xiaoyue Sun, Nie Qing, Lingxin Zhu, Zijun Wang et autres

Emerging clinical evidence has established a significant correlation between non-alcoholic steatohepatitis (NASH) and periodontitis severity, yet the causative relationship remains unclear. This study aims to investigate the direct impact of NASH on periodontitis progression and underlying mechanisms in vivo and in vitro. …

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Mdivi-1 Inhibits Pink1/Parkin-Dependent Mitophagy To Alleviate Osteolysis

Xiaoyue Sun, Jingjing Yu, Qing Nie, Lingxin Zhu et autres

Wear particle-induced aseptic craniofacial osteolysis around the implant-bone interface affects the prognosis of various implants. This study aims to explore the effects of the PINK1/Parkin pathway involved in mitochondrial quality control and its inhibitor Mdivi-1 on osteoclast-mediated physiological bone homeostasis and their …

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The Impact of Effective Dose to Immune Cells and Platelet-to-Lymphocyte Ratio on Lymphopenia and Prognosis in Patients with Unresectable Locally Advanced Non-Small Cell Lung Cancer

Hong Yang, Juncheng Ma, Chen Tian, J. Zhang et autres

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