Emily Redmond

Discovery and Optimization of Selective Inhibitors of Large Tumor Suppressor Kinases LATS1 and 2 for In Vivo Investigation of the Hippo-YAP Pathway in Tissue Regeneration

Kenji Namoto, Eric Vangrevelinghe, Rainer Machauer, Dirk Behnke et autres

Large Tumor Suppressor kinases LATS1 and 2 (LATS1/2) are serine/threonine kinases and core regulators of the Hippo-YAP pathway. Inhibition of LATS1/2 promotes nuclear translocation of nonphosphorylated YAP, thereby initiating a downstream cascade promoting cell proliferation. We set out to investigate the potential …

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Structure of saguaro cactus virus 3′ translational enhancer mimics 5′ cap for eIF4E binding

Manju Ojha, Jeff Vogt, Naba Krishna Das, Emily Redmond et autres

The genomes of several plant viruses contain RNA structures at their 3′ ends called cap independent translation enhancers (CITEs) that bind the host protein factors such as mRNA 5′ cap-binding protein eIF4E for promoting cap-independent genome translation. However, the structural basis of …

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Home- and Community-Based Services: A Comparison of Brain Injury Waivers Across the United States

Emily Redmond

OBJECTIVE: Adults and children who experience brain injury may need services and support when they return to the community. Home- and community-based services waivers are one way to access those supports. Brain injury waivers do not exist in every state, and variations …

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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

Kenji Namoto, Clara Baader, Vanessa Orsini, Alexandro Landshammer et autres

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Structure of saguaro cactus virus 3′ translational enhancer mimics 5′ cap for eIF4E binding

Manju Ojha, Jeff Vogt, Naba Krishna Das, Emily Redmond et autres

The genomes of several plant viruses contain RNA structures at their 3' ends called cap-independent translation enhancers (CITEs) that bind the host protein factors such as mRNA 5' cap-binding protein eIF4E for promoting cap-independent genome translation. However, the structural basis of such …

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Abstract 1670: The crystal structure of a PTE RNA element from a cactus virus that binds human eIF4E

Manju Ojha, Emily Redmond, Deepak Koirala

Hitting Pause: How User Perceptions of Collaborative Playlists Evolved in the United States During the COVID-19 Pandemic

So Yeon Park, Emily Redmond, Jonathan C Berger, Blair Kaneshiro

Through collaborative playlists (CPs), streaming platform users have co-curated music together for various purposes for over a decade. As the COVID-19 pandemic has transformed how people come together through technology and engage with music, CPs have also taken on new roles and …

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Farm Suicides in Wisconsin, 2017–2018: Preliminary Findings and a Call for Future Research

Bryan P. Weichelt, Rick Burke, Emily Redmond, John M. Shutske

Studies across the last few decades have consistently found farmers and farmworkers at an elevated risk of death by suicide compared to other occupational groups in the United States. Still, there is currently no comprehensive national surveillance system for agricultural-related injuries or …

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Stakeholders’ Consumption of Agricultural Injury Reports from News Media: A Six-Year Analysis of Website Usage and Visitor Analytics

Rick Burke, Matthew Pilz, Emily Redmond, Serap Görücü et autres

AgInjuryNews.org is a news report-based, online sentinel surveillance dataset that has provided publicly available news and media reports of agricultural injuries since early 2015. In the 6 years since its inception, AgInjuryNews.org has hosted 12,897 unique visitors and has collected 997 user …

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Coding agricultural injury: Factors affecting coder agreement

Serap Görücü, Bryan P. Weichelt, Emily Redmond, Dennis J. Murphy

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JA:2021-25. Increasing Efficiency and Reliability of Agricultural Injury and Fatality Coding with Standard Operating Procedures: Lessons Learned from AgInjuryNews.org

Emily Redmond, Serap Görücü, Megan Sauer, Rick Burke et autres

Purpose: News media reports of agricultural injuries can be useful to better inform safety and health stakeholders and prevention efforts. These data are particularly useful for youth incidents, since the National Institute of Occupational Safety and Health discontinued their survey-based agriculture surveillance …

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JA:2021-3. Dissemination and Adoption of AgInjuryNews.org: A Publicly Available Collection of Agricultural Injury Media Reports

Rick Burke, Matthew Pilz, Emily Redmond, Megan Sauer et autres

Purpose: Agriculture, Fishing, and Forestry (AFF) is the most dangerous occupation in the United States with 22.8 fatalities per 100,000 workers and a youth fatality rate of 28.21 per 100,000 workers as of 2017. As of 2015, the US Bureau of Labor …

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