Accès ouvert
2026
article
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan Carlos Oliveros et autres
Most neurodevelopmental disorders (NDDs), including intellectual disability, epilepsy, and autism spectrum disorder (ASD), exhibit marked sex differences in risk, incidence, prognosis, and clinical presentation. Increasing evidence suggests that these disorders often originate from alterations in circuit formation that occur during critical developmental …
es, us
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Additional file 3. Supplementary Tables S15-21. Related to Figures 1 to 5. Overrepresentation analysis of differentially expressed genes in the different comparisons as indicated in the upper cell on each individual table-sheet.
lk, us
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Additional file 2. Supplementary Tables S1-14. Related to Figures 1 to 5. List and information of differentially expressed genes compared as indicated in the upper cell on each individual table-sheet.
lk, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Additional file 1: Figure S1. Validation of Cux1 conditional knock-out mouse model. A) DNA constructions employed in generating and characterizing Cux1f and Cux1Δ23 alleles. B) Schematic representation of Cux1 used in this study. A ssDNA containing Cux1 exon 23 sequence flanked by …
lk, us
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Additional file 2. Supplementary Tables S1-14. Related to Figures 1 to 5. List and information of differentially expressed genes compared as indicated in the upper cell on each individual table-sheet.
lk, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Additional file 1: Figure S1. Validation of Cux1 conditional knock-out mouse model. A) DNA constructions employed in generating and characterizing Cux1f and Cux1Δ23 alleles. B) Schematic representation of Cux1 used in this study. A ssDNA containing Cux1 exon 23 sequence flanked by …
lk, us
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Additional file 3. Supplementary Tables S15-21. Related to Figures 1 to 5. Overrepresentation analysis of differentially expressed genes in the different comparisons as indicated in the upper cell on each individual table-sheet.
lk, us
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Abstract Most neurodevelopmental disorders (NDDs), including intellectual disability, epilepsy, and autism spectrum disorder (ASD), exhibit marked sex differences in risk, incidence, prognosis, and clinical presentation. Increasing evidence suggests that these disorders often originate from alterations in circuit formation that occur during critical …
lk, us
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Elia Marcos-Grañeda, Fernando Martín-Fernández, Linnea A. Weiss, Juan C. Oliveros et autres
Abstract Most neurodevelopmental disorders (NDDs), including intellectual disability, epilepsy, and autism spectrum disorder (ASD), exhibit marked sex differences in risk, incidence, prognosis, and clinical presentation. Increasing evidence suggests that these disorders often originate from alterations in circuit formation that occur during critical …
lk, us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Henry Oppermann, Elia Marcos-Grañeda, Linnea A. Weiss, Christina A. Gurnett et autres
Abstract Heterozygous, pathogenic CUX1 variants are associated with global developmental delay or intellectual disability. This study delineates the clinical presentation in an extended cohort and investigates the molecular mechanism underlying the disorder in a Cux1 +/− mouse model. Through international collaboration, we …
de, es, us, dk, fr, gb, ca, it, at, ch
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Henry Oppermann, Elia Marcos-Grañeda, Linnea A. Weiss, Christina A. Gurnett et autres
Abstract Heterozygous, pathogenic CUX1 variants are associated with global developmental delay or intellectual disability. This study delineates the clinical presentation in an extended cohort and investigates the molecular mechanism underlying the disorder in a Cux1+/− mouse model. Through international collaboration, we assembled …
de, dk, fr, gb, us, it, ca, at, ch
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
Stella Pappa, Natàlia Padilla, Simona Iacobucci, Marta Vicioso et autres
Histone H3 lysine 9 methylation (H3K9me) is essential for cellular homeostasis; however, its contribution to development is not well established. Here, we demonstrate that the H3K9me2 demethylase PHF2 is essential for neural progenitor proliferation in vitro and for early neurogenesis in the …
es
(code pays fourni par la source)