Sara Frosth

Cross‐protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

Romain Paillot, Tim Newton, Sonia González Medina, Sara Frosth et autres

BACKGROUND: Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. OBJECTIVES: To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with …

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Cross-protective effect of Strangvac during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

Romain Paillot, J. Richard Newton, Sonia Carolina González-Medina, Sara Frosth et autres

Background: Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objectives: To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with …

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Closing the Stable Door on Strangles: Serological Responses of Vaccinated Horses on a Farm Following the Arrival of a New Horse

Erika Rask, Francesco Righetti, Joakim Bjerketorp, Sara Frosth et autres

Infection of susceptible horses with Streptococcus equi subspecies equi (S. equi), the causative agent of strangles, is associated with commingling. Exposure may occur among horses at equestrian events, sales, or horses moved among different equine stabling environments. Strangles can affect all horses …

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Reining in strangles: Absence of disease in horses vaccinated with a DIVA‐compatible recombinant fusion protein vaccine, Strangvac, following natural exposure to Streptococcus equi subspecies equi

Gittan Gröndahl, Francesco Righetti, Anna Aspán, Joakim Bjerketorp et autres

BACKGROUND: Strangles, caused by Streptococcus equi subspecies equi (S. equi), is a prevalent infectious disease of horses. This is the first report on the use of a new vaccine, Strangvac, in a natural outbreak of strangles. OBJECTIVES: To measure the effects of …

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Closing the Stable Door on Strangles: Serological Responses of Vaccinated Horses in a Farm Following the Arrival of a New Horse

Erika Rask, Francesco Righetti, Joakim Bjerketorp, Sara Frosth et autres

Infection of horses with Streptococcus equi subspecies equi (S. equi), the causative agent of strangles, is associated with the movement of horses from one farm to another, or the attendance of equestrian events and sales. Strangles can affect all horses on a …

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Author response for "Reining in strangles: absence of disease in horses vaccinated with a DIVA compatible recombinant fusion protein vaccine, Strangvac, following natural exposure to Streptococcus equi subspecies equi"

Gittan Gröndahl, Francesco Righetti, Anna Aspán, Joakim Bjerketorp et autres

Neutralisation of the Immunoglobulin-Cleaving Activity of Streptococcus equi Subspecies equi IdeE by Blood Sera from Ponies Vaccinated with a Multicomponent Protein Vaccine

Francesco Righetti, Karina Hentrich, Margareta Flock, Sara Frosth et autres

Background: Streptococcus equi subspecies equi (S. equi) is the cause of strangles, one of the most prevalent diseases of horses worldwide. The disease is characterised by fever and the formation of abscesses in the lymph nodes of the head and neck, which …

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Reining in strangles: absence of disease in horses vaccinated with a DIVA compatible recombinant fusion protein vaccine, Strangvac, following natural exposure to Streptococcus equi subspecies equi

Gittan Gröndahl, Francesco Righetti, Anna Aspán, Joakim Bjerketorp et autres

Background: Strangles, caused by Streptococcus equi subspecies equi ( S. equi ), is a prevalent infectious disease of horses. This is the first report on protection conferred by a new vaccine, Strangvac, against natural infection. Objectives: To measure the effects of Strangvac …

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Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population

Abigail McGlennon, Kristien Verheyen, J. R. Newton, Andries J. van Tonder et autres

BACKGROUND: Strangles (Streptococcus equi infection) remains endemic in the UK, with ~300 laboratory diagnoses annually. Sub-clinically infected long-term carriers are considered a key driver of endemicity. Analysing genomes of circulating strains could provide valuable transmission insights of this pathogen. OBJECTIVES: To determine …

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Corrigendum: Progressive evolution of Streptococcus equi from Streptococcus equi subsp. zooepidemicus and adaption to equine hosts

Hayley Wilson, Jianbao Dong, Andries J. van Tonder, Christopher Ruis et autres

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks …

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Role of Staphylococcus aureus colonization in burn patients

Susanne Sütterlin, Marie Lindblad, Eva Tano, Sara Frosth et autres

Objectivs Staphylococcus aureus is an important pathogen in burn patients and contributes to mortality, however, the role of colonization with S. aureus in the course of the disease is less well described. Methods The study aimed to determine the frequency of S. …

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Sow vaccination with a novel recombinant protein vaccine protects piglets against Streptococcus suis infection

Sara Frosth, David Reddick, Francesco Righetti, Joakim Bjerketorp et autres

Streptococcus suis is a severe zoonotic pathogen affecting weaned piglets. No commercial vaccine that provides protection against S. suis is available. A prototype vaccine, tentatively called VASIP (Vaccine Against Streptococcus suis Infection in Pigs), composed of five recombinant fusion proteins, encompassing 23 …

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