Accès ouvert
2024
article
OpenAlex
Han L. Tan, Luping Yin, Yuqi Tan, Jessica Ivanov et autres
Abstract Leptin is an adipose tissue hormone that maintains homeostatic control of adipose tissue mass by regulating the activity of specific neural populations controlling appetite and metabolism 1 . Leptin regulates food intake by inhibiting orexigenic agouti-related protein (AGRP) neurons and activating …
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Santiago R. Unda, Lisa E. Pomeranz, Roberta Marongiu, Xiaofei Yu et autres
Here, we report a magnetogenetic system, based on a single anti-ferritin nanobody-TRPV1 receptor fusion protein, which regulated neuronal activity when exposed to magnetic fields. Adeno-associated virus (AAV)–mediated delivery of a floxed nanobody-TRPV1 into the striatum of adenosine-2a receptor–Cre drivers resulted in motor …
us, cn, be
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Han L. Tan, Luping Yin, Yuqi Tan, Jessica Ivanov et autres
Abstract Leptin is an adipose tissue hormone that maintains homeostatic control of adipose tissue mass by regulating the activity of specific neural populations controlling appetite and metabolism 1 . Leptin regulates food intake by inhibiting orexigenic agouti-related protein (AGRP) neurons and activating …
us, pl
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Putianqi Wang, Noelyn M. Kljavin, Thi Thu Thao Nguyen, Elaine E. Storm et autres
us, fr
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Santiago R. Unda, Lisa E. Pomeranz, Roberta Marongiu, Xiaofei Yu et autres
Abstract Here we report a novel suite of magnetogenetic tools, based on a single anti-ferritin nanobody-TRPV1 receptor fusion protein, which regulated neuronal activity when exposed to magnetic fields. AAV-mediated delivery of a floxed nanobody-TRPV1 into the striatum of adenosine 2a receptor-cre driver …
us, pl, cn, be
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Lisa E. Pomeranz, Rosemary Li, Xiaofei Yu, Leah Kelly et autres
Abstract The ability to precisely control the activity of defined cell populations enables studies of their physiological roles and may provide therapeutic applications. While prior studies have shown that magnetic activation of ferritin-tagged ion channels allows cell-specific modulation of cellular activity, the …
us, cn, be
(code pays fourni par la source)
Accès ouvert
2020
erratum
OpenAlex
Paul Müller, Marc Schneeberger, Fanny Matheis, Putianqi Wang et autres
us, jp
(code pays fourni par la source)
2020
article
OpenAlex
Putianqi Wang, Ken H. Loh, Michelle Wu, Donald A. Morgan et autres
us, cn
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Paul Müller, Marc Schneeberger, Fanny Matheis, Putianqi Wang et autres
us, jp
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
Putianqi Wang
Our lab discovered a novel enzyme, arylacetamide deacetylase-like 1 (AADACL1) that regulates lipid metabolism and platelet activation in human platelets. Inhibition of AADACL1 by a small molecule inhibitor JW480 decreases platelet aggregation in response to platelet agonists such as collagen. Our work …
us
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
Marc Schneeberger, Luca Parolari, Tania Das Banerjee, Varun Bhave et autres
us, fr
(code pays fourni par la source)