Qinghua Min

Can radiology requisition quality reflect clinical reasoning? Insights from a RI-RADS evaluation of emergency CT referrals

Xian‐Wei Liu, Zhengguang Xiao, Qinghua Min, Tianhao Wu et autres

OBJECTIVES: To determine radiology requisition quality using reason for exam imaging reporting and data system (RI-RADS), and the associated clinical variables, and whether it can reflect the clinical reasoning quality in emergency CT referrals. MATERIALS AND METHODS: This single-center retrospective study randomly …

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Study on the Influence of Blasting Construction of Double-Layer Superimposed Primary Support Arch Cover Method on the Surrounding Environment

Xinping Guo, Annan Jiang, Qinghua Min

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Research progress on the premature ovarian failure caused by cisplatin therapy

Zelin Li, Haodong Qi, Zhengyang Li, Yuxuan Bao et autres

Cisplatin is a common anticancer drug able to kill tumor cells, but it causes adverse reactions in the kidney, digestive tract, and other systems. The antitumor effects of cisplatin are mainly due to its ability to bind to the DNA in tumor …

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Research on Optimization Design of Tunnel Blasting Scheme Adjacent to Buildings

Kuan Ren, Annan Jiang, Xinping Guo, Qinghua Min

The section of Jialingjiang Road Station to Xiangjiang Road Station along Qingdao Metro Line 13 is located in Qingdao, China. All of them show obvious characteristics, being soft on the top and hard on the bottom, and the interval tunnel is faced …

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Safety and antitumour activity of cadonilimab, an anti-PD-1/CTLA-4 bispecific antibody, for patients with advanced solid tumours (COMPASSION-03): a multicentre, open-label, phase 1b/2 trial

Xiangyu Gao, Nong Xu, Ziyu Li, Lin Shen et autres

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Macroscopic experimental and constitutive model research on tensile properties of sandstone after high-temperature treatment

Haopeng Jiang, Annan Jiang, Fengrui Zhang, Yunpeng Feng et autres

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Back Analysis of Surrounding Rock Parameters of Large-Span Arch Cover Station Based on GP-DE Algorithm

Zheng Fu, Annan Jiang, Xinping Guo, Qinghua Min et autres

Due to the characteristics of soil–rock composites and large-span arches, the surrounding rock parameters of stations are difficult to obtain accurately under soft upper and hard lower geological conditions when the arch cover method is used to carry out the construction of …

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Quantitative Proteomic Analysis of Plasma Exosomes to Identify the Candidate Biomarker of Imatinib Resistance in Chronic Myeloid Leukemia Patients

Mei‐Yong Li, Zhao Cui, Lian Chen, Fangyi Yao et autres

BACKGROUND: Imatinib (IM), a tyrosine kinase inhibitor (TKI), has markedly improved the survival and life quality of chronic myeloid leukemia (CML) patients. However, the lack of specific biomarkers for IM resistance remains a serious clinical challenge. Recently, growing evidence has suggested that …

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PPARγ induces the paroxysm of endometriosis by regulating the transcription of MAT2A gene.

Shun Zhang, Lingling Zhuang, Qian Liu, Xiaolin Yu et autres

OBJECTIVE: To investigate the molecular mechanism of PPARγ impacting the paroxysm of endometriosis. METHODS: Immunohistochemistry, qRT-PCR and Western Blot were used to determine the expression level of PPARγ and MAT2A in Eu, Ec and normal endometrial tissue (control). ESC and NSC were …

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Rosiglitazone affects the progression of surgically‑induced endometriosis in a rat model

Shun Zhang, Lingling Zhuang, Qian Liu, Xiaolin Yu et autres

Endometriosis is closely associated with inflammatory reactions and angiogenesis. Whether PPARγ is a target for the treatment of endometriosis remains unknown. The present study was designed to investigate the impact of a PPARγ agonist (rosiglitazone, RSG) on endometriosis in a rat model …

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Correction of Bcl‐x splicing improves responses to imatinib in chronic myeloid leukaemia cells and mouse models

Jing Zhang, Yan Wang, Shuqi Li, Le Fang et autres

Imatinib mesylate (IM) resistance has become a major clinical problem for chronic myeloid leukaemia (CML). It is known that Bcl-x splicing is deregulated and is involved in multiple malignant cancer initiation and chemotherapy resistance, including CML. The aim of the present study …

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K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711

Yuhuan Jiang, Jing Liu, Lin Jin, Shuqi Li et autres

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