Accès ouvert
2026
article
OpenAlex
Layla K. Mahdi, Gareth S Denyer, Maurizio Costabile
Identifying disease-causing microorganisms in patient samples is a cornerstone activity in clinical diagnostic microbiology laboratories. This process relies on traditional microbiological techniques alongside advanced technological methods, such as matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF). Despite its growing prevalence in diagnostic settings, …
au
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Accès ouvert
2025
article
OpenAlex
Maurizio Costabile, Sheree Bailey, Gareth S Denyer
Abstract Description A hemocytometer is a key piece of laboratory equipment typically used in diagnostic and immunology research laboratories to enumerate white blood cells. The accurate quantification of cell density is essential to ensure accurate numbers of cells are added to assays …
au
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Accès ouvert
2025
article
OpenAlex
Maurizio Costabile, Gareth S Denyer
Abstract Description Neutrophils are key cells involved with innate immunity. Following injury, neutrophils follow a chemotactic gradient to phagocytose pathogens, such as bacteria. Several well-controlled events are required, and defects at any stage present as an immune deficiency. At UniSA, immunology is …
au
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Accès ouvert
2025
article
OpenAlex
Kylie E. Webster, Helen Elizabeth Ritchie, Gareth S Denyer
Abstract Description T cell development is an important foundational concept for undergraduate immunology. A good understanding of this process equips students to better appreciate the central tenets of immunology, such as self/non-self discrimination, immune tolerance and MHC restriction. Like many undergraduate immunology …
au
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Accès ouvert
2025
article
OpenAlex
Maurizio Costabile, Gareth S Denyer
Neutrophils are essential cellular components of innate immunity. After injury, they migrate into tissues following chemotactic gradients to phagocytose pathogens or respond to tissue damage. This multistep process is tightly regulated, and defects at any stage can lead to increased bacterial infections. …
au
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Accès ouvert
2025
article
OpenAlex
Matthew Clemson, Alice Huang, Gareth S Denyer, Maurizio Costabile
The teaching of laboratory skills to undergraduate students is central to all experimental sciences. In this setting, students must understand the experimental procedures as well as the fundamental principle(s) being demonstrated, all while learning within a limited time. Other limiting factors include …
au
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2025
article
OpenAlex
Chris B. Della Vedova, Gareth S Denyer, Maurizio Costabile
Innovative approaches to teaching genetics are essential for improving student engagement and comprehension in this challenging field. Laboratory-based instruction enhances engagement with the subject while fostering the development of practical competencies and deepening comprehension of theoretical concepts. However, constraints on time and …
au
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Accès ouvert
2024
article
OpenAlex
Helen Elizabeth Ritchie, Gareth S Denyer, Kylie E. Webster
Undergraduate courses in immunology are content-heavy and combined with a new, complex vocabulary, can be an overwhelming subject for students. In-class active learning approaches have been found to improve understanding of difficult concepts in science, technology, engineering and mathematics (STEM) disciplines; however, …
au
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Accès ouvert
2024
article
OpenAlex
Maurizio Costabile, Sheree Bailey, Gareth S Denyer
A hemocytometer is a key piece of laboratory equipment typically used in diagnostic and immunology research laboratories to enumerate white blood cells. The accurate quantification of cell density is essential to ensure accurate numbers of cells are added to assays to generate …
au
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Accès ouvert
2022
article
OpenAlex
Layla K. Mahdi, Gareth S Denyer, Maria C. Caruso, Maurizio Costabile
Determining the antibiotic sensitivity of disease-causing microorganisms is a fundamental process in a clinical microbiology laboratory. With the continued use of antibiotics, the emergence of antibiotic resistance has become a significant health issue. However, the principles and laboratory testing to determine antibiotic …
au
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Accès ouvert
2021
article
OpenAlex
Courtney B. Hilton, Micah B. Goldwater, Dale Hancock, Matthew Clemson et autres
A critical goal for science education is to design and implement learning activities that develop a deep conceptual understanding, are engaging for students, and are scalable for large classes or those with few resources. Approaches based on peer learning and online technologies …
au, us
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Accès ouvert
2021
article
OpenAlex
Alice Huang, Dale Hancock, Matthew Clemson, Giselle C. Yeo et autres
Production of high-quality multiple-choice questions (MCQs) for both formative and summative assessments is a time-consuming task requiring great skill, creativity and insight. The transition to online examinations, with the concomitant exposure of previously tried-and-tested MCQs, exacerbates the challenges of question production and …
au, nz
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