Accès ouvert
2026
article
OpenAlex
Michaela Kuhlen, Samuele Naviglio, Raphael Hirtz, Calogero Virgone et autres
OBJECTIVE: The objective of this work was to summarize current evidence and practical management considerations for thyroid nodules in children and adolescents with cancer predisposition syndromes (CPSs), focusing on follicular cell-derived nodules and non-medullary thyroid carcinoma (NMTC). METHODS: We synthesized current paediatric …
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Accès ouvert
2026
article
OpenAlex
Francesca Alt
Zusammenfassung Individuelle Heilversuche bei Kindern stellen paradigmatische Entscheidungssituationen dar, in denen medizinische Indikation, prognostische Unsicherheit, elterliche Stellvertretung und kindliche Vulnerabilität normativ vermittelt werden müssen. Sie treten nicht ausschließlich in palliativen Situationen auf, sondern auch in Konstellationen begrenzter Evidenz, etwa bei der Übertragung …
de
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Accès ouvert
2026
article
OpenAlex
Hamideh Frühwein, Susanne Theis, Marie Neu, Francesca Alt
Cancer remains one of the leading causes of premature mortality in Europe, with nearly half of all cases attributable to modifiable risk factors. While preventive strategies are well-established, their implementation across European health systems remains fragmented, underfunded, and insufficiently aligned with population …
de
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Accès ouvert
2026
article
OpenAlex
Moein Kermani, Sebastian Maxeiner, Francesca Alt, Nicole Ziegler et autres
Introduction The B-cell-specific marker CD20 is expressed in various B-cell malignancies, including B-cell acute lymphoblastic leukemia (B-ALL) and serves as a key target for immunotherapies. Reduced or absent CD20 expression has been associated with diminished responses to anti-CD20 antibodies and CD20 directed …
de
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Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, A. C. Balduzzi et autres
BACKGROUND: The FORTEe randomised controlled trial (NCT05289739) investigates an exercise intervention for children and adolescents undergoing cancer treatment. Conducting research with this vulnerable population poses unique ethical challenges, including participant burden, child autonomy, and parental decision-making. This study explored the ethical experiences …
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Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Supplementary Material 3.
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Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Abstract Background The FORTEe randomised controlled trial (NCT05289739) investigates an exercise intervention for children and adolescents undergoing cancer treatment. Conducting research with this vulnerable population poses unique ethical challenges, including participant burden, child autonomy, and parental decision-making. This study explored the ethical …
de, gb, fr, dk, es, it, si
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Supplementary Material 2.
de, gb, fr, dk, es, it, si
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Accès ouvert
2026
other
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Abstract Background The FORTEe randomised controlled trial (NCT05289739) investigates an exercise intervention for children and adolescents undergoing cancer treatment. Conducting research with this vulnerable population poses unique ethical challenges, including participant burden, child autonomy, and parental decision-making. This study explored the ethical …
de, gb, fr, dk, es, it, si
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Supplementary Material 1.
de, gb, fr, dk, es, it, si
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Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Supplementary Material 1.
de, gb, fr, dk, es, it, si
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Francesca Alt, Elias Dreismickenbecker, Francesca Lanfranconi, Adriana Balduzzi et autres
Supplementary Material 2.
de, gb, fr, dk, es, it, si
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