Martha Sosa‐Macías

Demographic History of Indigenous Populations in Mexico Explored Through Whole Mitogenome Analysis

Marlen Flores-Huacuja, Meradeth Snow, Jazmín Ramos‐Madrigal, Cecilia Contreras-Cubas et autres

Mitochondrial DNA plays a key role in understanding the demographic history of human populations. Particularly in the Americas#nine widespread Native American specific mitochondrial lineages have been identified. Here we performed the whole mitogenome sequencing of 572 Indigenous individuals from 60 populations spanning …

mx, us, dk, es (code pays fourni par la source)

CYP2C:TG Haplotype in Native Mexicans, Molecular Ancestry and Its Implications for CYP2C19 Genotype–Phenotype Correlation

Carla González de la Cruz, Nadine de Godoy Torso, Juan Antonio Villatoro-García, Carmen Mata-Martín et autres

Background: Recent studies have associated the presence of the CYP2C:TG haplotype with increased metabolism of CYP2C19 substrates such as escitalopram and sertraline, suggesting a potential regulatory interaction between CYP2C18 and CYP2C19. However, this association has not been demonstrated for other CYP2C19 substrates. …

es, br, mx (code pays fourni par la source)

The triglyceride and glucose index as a surrogate biomarker for the identification of metabolic syndrome in Mexican Indigenous populations

Luis E. Simental‐Mendía, Martha Sosa‐Macías, Laura Jazel Barragán‐Zuñiga, Carlos Galavíz-Hernández et autres

mx (code pays fourni par la source)

Sociodemographic and clinical profiles associated with preeclampsia: Comparison between Argentinean and Mexican women cohorts

Mariano Reynoso, Martha Sosa‐Macías, Laura Jazel Barragán‐Zuñiga, Alicia E. Damiano et autres

mx, ar (code pays fourni par la source)

EVALUATION OF NUCLEOTIDE VARIATIONS IN THE ADORA2A GENE AND THEIR ASSOCIATION WITH PREECLAMPSIA

Perla I. Valenzuela-Torres, Carlos Escudero, Martha Sosa‐Macías, Ismael Lares et autres

mx, cl (code pays fourni par la source)

Sex-specific effect of prenatal fluoxetine administration on the expression of genes involved in placental serotonin regulation.

Jorge Eduardo Sifuentes-García, Laura Jazel Barragán‐Zuñiga, Carlos Galavíz-Hernández, Claudia I. Gamboa‐Gómez et autres

mx (code pays fourni par la source)

Prevalence of Obesity, Diabetes, Hypertension, and Cardiovascular Risk Factors among Mexican Indigenous Groups

Luis E. Simental‐Mendía, Martha Sosa‐Macías, Laura Jazel Barragán‐Zuñiga, Carlos Galavíz-Hernández et autres

Objective. To describe the prevalence of obesity, diabetes, hypertension, and cardiovascular risk factors in the Indigenous populations of Northwest Mexico. Method. A cross-sectional study was conducted among Indigenous and rural Mestizo populations of Northwest Mexico, including Coras, Huicholes, Mexicaneros, Tarahumaras, and Tepehuanos, …

mx, ec (code pays fourni par la source)

The triglycerides and glucose index is strongly associated with fatty liver in Mexican Indigenous populations

Luis E. Simental‐Mendía, Martha Sosa‐Macías, Laura Jazel Barragán‐Zuñiga, Carlos Galavíz-Hernández et autres

mx (code pays fourni par la source)

PLAC8 Expression Regulates Trophoblast Invasion and Conversion into an Endothelial Phenotype (eEVT)

Laura Jazel Barragán‐Zuñiga, Rodrigo Escalona‐Rivano, Catalina Cordero-Tirado, Martha Sosa‐Macías et autres

PLAC8, expressed by interstitial extravillous trophoblasts (iEVTs), plays a crucial role in trophoblast invasion, differentiation, and immunotolerance. Its dysregulation may contribute to pregnancy complications, such as preeclampsia. This study investigates the role of PLAC8 in trophoblast invasiveness and endothelial-like differentiation under different …

mx, cl (code pays fourni par la source)

Association of (TG)n(GA)m repeats downstream CMA1 gene with preeclampsia in Mexican population

Laura Jazel Barragán‐Zuñiga, Martha Sosa‐Macías, Luis E. Simental‐Mendía, Jazel Barragán-Zuñiga et autres

mx, cr (code pays fourni par la source)

CYP2C19 genotype-phenotype correlation: current insights and unanswered questions

Nadine de Godoy Torso, Fernanda Rodrigues‐Soares, Catalina Altamirano-Tinoco, Ronald Ramírez‐Roa et autres

Abstract The CYP2C19 enzyme is implicated in the metabolism of several clinically used drugs. Its phenotype is usually predicted by genotyping and indicates the expected enzymatic activity for each patient. However, with a few exceptions, CYP2C19 genotyping has not resulted in a …

br, es, ni, mx, ec (code pays fourni par la source)

Effect of fluoxetine on placental expression of genes involved in serotonin homeostasis

Jorge Eduardo Sifuentes-García, Sergio Rocha-Márquez, Marisela Aguilar-Durán, Blanca Patricia Lazalde-Ramos et autres

mx (code pays fourni par la source)