Wenda Zou

Causal relationships between gut microbiota and urothelial carcinoma mediated by inflammatory cytokines and blood cell traits identified through Mendelian randomization analysis

Xipeng Wu, Wenda Zou, Ziwei Liu

BACKGROUND: The role of gut microbiota in tumorigenesis has gained significant attention in recent years. This study aimed to investigate the causal relationship between gut microbiota and three types of urothelial carcinoma (renal pelvic cancer [RPC], urothelial carcinoma [UC], and bladder cancer …

cn (code pays fourni par la source)

A case report of a successful pregnancy after intracytoplasmic sperm injection when all oocytes contained abnormal inclusions in the perivitelline space

Juan Peng, Wenda Zou, Liyu Zhu, Xinlin Guo et autres

BACKGROUND: The relationship between oocyte morphology and developmental potential has been a hot research topic in assisted reproductive technology (ART). Whether inclusions in the perivitelline space (PVS) affect ART outcomes remains controversial. CASE PRESENTATION: We present a case report of a 34-year-old …

cn (code pays fourni par la source)

Probiotics Combined with Metformin Improves Sperm Parameters in Obese Male Mice through Modulation of Intestinal Microbiota Equilibrium

Dan Liu, Xiaolong Han, Wenda Zou, Zhenyu Yang et autres

cn (code pays fourni par la source)

The relationship between immune cells and prostate cancer, and the mediating role of metabolites: a Mendelian randomization study

Xipeng Wu, Wenda Zou, Ziwei Liu

Research has demonstrated the significant involvement of immune cells in the development and progression of prostate cancer (PCa). However, the precise causal relationship between immune cells and PCa remains unclear. This study utilized bidirectional Mendelian randomization (MR) analysis to investigate the causal …

cn (code pays fourni par la source)

The relationship between immune cells and prostate cancer, and the mediating role of metabolites: a Mendelian randomization study

Xipeng Wu, Wenda Zou, Ziwei Liu

Abstract Background Research has demonstrated the significant involvement of immune cells in the development and progression of prostate cancer (PCa). However, the precise causal relationship between immune cells and PCa remains unclear. Methods This study utilized bidirectional Mendelian randomization(MR)analysis to investigate the …

cn (code pays fourni par la source)

Sequential embryo transfer combined with intrauterine perfusion improved pregnancy outcomes in patients with recurrent implantation failure

Wenda Zou, Dan Liu, Juan Peng, Zhijing Tang et autres

OBJECTIVE: To compare the application of sequential embryo transfer, cleavage embryo transfer, and blastocyst transfer combined with intrauterine perfusion in frozen-thawed embryo transfer cycles in patients with recurrent implantation failure to provide a reference for reproductive clinicians. METHODS: The 166 patients who …

cn (code pays fourni par la source)

ANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway and interacting with ESM1

Yukun Li, Anbo Gao, Tian Zeng, Dan Liu et autres

BACKGROUND: Ovarian cancer (OC) is a malignant neoplasm that displays increased vascularization. Angiopoietin-like 4 (ANGPTL4) is a secreted glycoprotein that functions as a regulator of cell metabolism and angiogenesis and plays a critical role in tumorigenesis. However, the precise role of ANGPTL4 …

cn (code pays fourni par la source)

Additional file 1 of ANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway and interacting with ESM1

Yukun Li, Anbo Gao, Tian Zeng, Dan Liu et autres

Additional file 1: Fig. S1. Prognostic significance of ARGs in OC patients. A Prognostic models were constructed by LASSO regression based on ARGs. B Lambda on abscissa, coefficients on ordinate. C The survival times, risk score, and signature expression in OC patients. …

cn (code pays fourni par la source)

Comprehensive Analyses and Experiments Confirmed IGFBP5 as a Prognostic Predictor Based on an Aging-genomic Landscape Analysis of Ovarian Cancer

Ting-Yu Fan, Lili Xu, Hongfeng Zhang, Juan Peng et autres

BACKGROUND: Ovarian cancer (OC) is one of the malignant diseases of the reproductive system in elderly women. Aging-related genes (ARGs) were involved in tumor malignancy and cellular senescence, but the specifics of these mechanisms in OC remain unknown. METHODS: ARGs expression and …

cn (code pays fourni par la source)

ANGPTL4 accelerates carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway and interacting with ESM1

Yukun Li, Anbo Gao, Tian Zeng, Qun-feng Zhang et autres

Abstract Ovarian cancer (OC) is a malignant neoplasm that displays increased vascularization. Angiopoietin-like 4 (ANGPTL4) is a secreted glycoprotein that functions as a regulator of cell metabolism and angiogenesis and plays a critical role in tumorigenesis. However, the precise role of ANGPTL4 …

cn (code pays fourni par la source)

Clinical characterization and immunosuppressive regulation of IL15RA in Kidney renal papillary cell carcinoma through 324 samples

Ziwei Liu, Wenda Zou, Yong Xu, Peng Wu

Abstract Stimulation of renal cell carcinoma with exogenous IL-15Rα, encoded by IL15RA, could induce epithelial-mesenchymal transition (EMT) and promote cell migration and invasion. To assess the validity of IL15RA in predicting the prognosis of kidney renal papillary cell carcinoma (KIRP) and to …

cn (code pays fourni par la source)

Meta-analysis of the relevance between sperm parameters and serum vitamin D levels in infertile men

Wenda Zou, Ziwei Liu, Juan Zhang

To systematically estimate the relevance between sperm parameters and serum vitamin D levels and the subsequent reproductive outcomes in men. PubMed, Web of Science and other databases were searched for studies that examined a possible correlation between serum vitamin D levels and …

cn (code pays fourni par la source)