Simen Foyn Nørstebø

IgM-mediated protection drives early B-cell activation and mucosal containment of Vibrio anguillarum in Atlantic cod (Gadus morhua)

Naomi Croft Guslund, Alexandra Jonsson, Anders Kristian Krabberød, Adrián López-Porras et autres

Background Atlantic cod lack functional MHC class II and CD4, raising fundamental questions about how vaccination generates protection in this species. Methods We combined single-cell transcriptomic profiling of splenic cells with qRT-PCR across complementary active vaccination and passive serum-transfer experiments to define …

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Welfare and Physiological Consequences of Non‐Lethal Blood Sampling From the Caudal Vasculature of Atlantic Salmon ( Salmo salar L.)

Harriet Romstad, Camilla Karlsen, Silje Stensby-Skjærvik, Alf Seljenes Dalum et autres

The objective of this study was to evaluate welfare and health effects following single and repeated non-lethal blood sampling from the caudal vasculature of Atlantic salmon. Two experiments were conducted at three different temperatures: a 6-week freshwater experiment with fish weighing 50-100 …

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Canine Providencia alcalifaciens: virulence factors and phylogenetic analysis of an emerging enteropathogen

Eiril Moen Soltvedt, Karin Lagesen, Simen Foyn Nørstebø, Sabrina Rodriguez-Campos et autres

In 2019, an outbreak of acute haemorrhagic diarrhoea (AHD) in dogs in Norway was linked to Providencia alcalifaciens . A marked increase in diarrhoeal cases in dogs during the autumn, along with the frequent identification of P. alcalifaciens in affected dogs, supports …

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Cell-specific organization and paralog divergence of erythropoietin signaling in Atlantic salmon

Thea Hjemsæter, Ida B. Johansen, Per Gunnar Fjelldal, Daniel J. Macqueen et autres

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Long-term colonization dynamics of probiotic Aliivibrio spp. in Atlantic Salmon (Salmo salar) following bath administration

Marius Steen Dobloug, Stanislav Iakhno, Simen Foyn Nørstebø, Øystein Evensen et autres

Ulcerative conditions present a major challenge in Norwegian salmon farming. Probiotic Aliivibrio species have previously been demonstrated to provide health benefits in both Atlantic salmon and lumpfish. This study aimed to investigate whether these bacteria could colonize Atlantic salmon following bath administration, …

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Antagonistic Mechanisms of Probiotic Aliivibrio sp. Strain Vl2 Against Moritella viscosa: Evidence from Co-cultivation and Targeted Transcriptomic Analysis

Marius Steen Dobloug, Stanislav Iakhno, Simen Foyn Nørstebø, Henning Rune Sørum

Winter ulcers, primarily caused by Moritella viscosa, represent a significant challenge for the Norwegian aquaculture industry. Effective control measures are hampered by the lack of effective vaccines and limited use of antibiotics, driven by the global effort to combat antibiotic resistance. Recent …

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Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4

Alexandra Jonsson, Adrián López-Porras, Simen Foyn Nørstebø, Naomi Croft Guslund et autres

The unique adaptive immune system of the Atlantic cod (Gadus morhua), with genetic loss of the mhc class II and cd4, poses questions about the protective role of specific antibodies in this species. We investigate the IgM response against Vibrio anguillarum, a …

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Characterization of the smoltification process and post-sea transfer stunts of Atlantic salmon (salmo salar) in full-scale intensive production

Alexander J. Hat. Figenschou, Hege Lund, Ian Mayer, Marit Bråten Svendby et autres

Stunting, characterized by impaired growth following seawater transfer, poses a significant challenge in the aquaculture of Atlantic salmon ( Salmo salar ). Stunts exhibit markedly reduced growth compared to normally developing conspecific individuals. This condition is associated with increased mortality and heightened …

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The cervical microbiome of ewe breeds with known divergent fertility following artificial insemination with frozen-thawed semen

Simen Foyn Nørstebø, Sabrina Rodríguez, Özgün C. O. Umu, Laura Abril-Parreño et autres

The use of artificial insemination (AI) with frozen-thawed semen in sheep is limited internationally due to low pregnancy rates. An exception is Norway, where high success rates routinely occur following vaginal deposition of frozen-thawed semen during natural estrus. Previous research suggests that …

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System- and fish-size-specific reference intervals for plasma analytes in Atlantic salmon (Salmo salar L.) reared in commercial fresh- and saltwater recirculating aquaculture systems: a descriptive study

Thomas Amlie, David Persson, Simen Foyn Nørstebø, Asgeir Østvik et autres

Introduction In aquaculture, clinical chemistry can be used pre-emptively to manage fish health and for early disease intervention. While less established in farmed fish compared to farmed terrestrial animals, it has been used for salmonid cage farming but is almost non-existent in …

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Characterization of the Smoltification Process and Post-Sea Transfer Stunts of Atlantic Salmon (Salmo Salar) in Full-Scale Intensive Production

Alexander J. Hat. Figenschou, Hege Lund, Ian Mayer, Marit Bråten Svendby et autres

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Long-Term Colonization Dynamics of Probiotic Aliivibrio spp. in Atlantic Salmon ( Salmo salar) Following Bath Administration

Marius Steen Dobloug, Stanislav Iakhno, Simen Foyn Nørstebø, Øystein Evensen et autres

Abstract Ulcerative conditions present a major challenge in Norwegian salmon farming. Probiotic Aliivibrio species have previously been demonstrated to provide health benefits in both Atlantic salmon and lumpfish, although the underlying mechanisms and the host-bacteria interactions remain unclear. This study aimed to …

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