Accès ouvert
2023
preprint
OpenAlex
Won-Jun Lim, Hyunjin M. Kim, YongHo Oh, Junhee Pyo
Abstract We aimed to uncover genetic factors affecting resistance to the cancer drug olaparib. To do this, we utilized multiomics matrix factorization (MOFA), a multiomics approach, to explore omic-based features that might become biomarker candidates. Our results showed that 17 damaging mutations, …
kr, us
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Accès ouvert
2013
article
OpenAlex
Hyunjin M. Kim, Michelle D. Smith, Jae‐Hun Kim, Mary Ann Caplen et autres
us
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Accès ouvert
2012
article
OpenAlex
Pauline C. Ting, Joe F. Lee, Nicolas Frederic Zorn, Hyunjin M. Kim et autres
us
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Accès ouvert
2010
article
OpenAlex
Elizabeth M. Smith, Steve Sorota, Hyunjin M. Kim, Brian A. McKittrick et autres
us
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2006
article
OpenAlex
Jeffrey R. Spencer, Martin Sendzik, Jason Oeh, Peter Sabbatini et autres
us
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2002
article
OpenAlex
Oren A. Scherman, Hyunjin M. Kim, Robert Howard Grubbs
The synthesis of a new methylene−(vinyl alcohol) copolymer, poly((vinyl alcohol) 2 - alt -methylene) (MVOH), by ring-opening metathesis polymerization with ruthenium catalysts is reported. Unsaturated cyclic 1,3-diols were protected with a di- tert -butylsilyl group to form strained cyclic olefins. The molecular …
us
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Accès ouvert
2002
article
OpenAlex
Govindaswami Ragupathi, Prashant P. Deshpande, Don M. Coltart, Hyunjin M. Kim et autres
There is mounting evidence to suggest that immunization-based strategies can be used to mobilize the human immune system against specific carbohydrate antigens displayed on the surface of cancer cells. Following isolation and identification, such antigens can be administered as conjugate vaccines. The …
us
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2001
article
OpenAlex
Hyunjin M. Kim, In Jong Kim, Samuel J. Danishefsky
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article …
us
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2000
article
OpenAlex
Hyunjin M. Kim, In Jong Kim, Samuel J. Danishefsky
The total syntheses of two octasaccharide antigens isolated from human milk, 1 and 2, and their corresponding allyl glycosides, 3 and 4, have been achieved by utilizing the glycal method. Convergent assembly of the core hexasaccharides and concurrent introduction of two alpha-L-fucosyl …
us
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1999
report
OpenAlex
Hyunjin M. Kim, Samuel Danishefshky
The immunological study of globo-H, a breast tumor associated carbohydrate antigen, has been producing promising results. As the demand for this antigen grows, the efficient production has become an urgent problem. We have been trying to solve this problem via two approaches: …
1999
article
OpenAlex
Govindaswami Ragupathi, Susan F. Slovin, Sucharita Adluri, Dalibor Sameš et autres
Osteoblasten: ja, Blutplättchen: nein! Knochenimplantate müssen sich mit dem umgebenden Gewebe verbinden, um möglichst gut einwachsen zu können. Ein neues Verfahren wird beschrieben, das auf der kovalenten Anknüpfung eines hochselektiven RGD-Peptides an Polymethylmethacrylat (PMMA) basiert (siehe Bild). Osteoblasten binden sehr effektiv an …
us
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1999
article
OpenAlex
Govindaswami Ragupathi, Susan F. Slovin, Sucharita Adluri, Dalibor Sameš et autres
Human trials on the globo H carbohydrate vaccine (see picture, KLH=the carrier protein keyhole limpet hemocyanin) show that it produces strong IgM, and in some cases IgG, responses in patients with progressive and recurrent prostate cancer. Furthermore, these antibodies not only recognize …
us
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