Rihab Nasr

Crossing Borders for Pathology Capacity Building in a Regional Setting: A Pediatric Oncology Initiative

Khaled M. Ghanem, Ayman Tawil, Sara Sinno, Teresa Santiago et autres

PURPOSE: Barriers to accurate histopathologic diagnosis in lower middle-income countries (LMIC) undermine appropriate patient outcomes. We report the results of a regional LMIC twinning initiative, with the support of a high-income country institution, for building capacity in histopathologic diagnosis of pediatric cancers. …

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Clinical Research Capacity Building in Pediatric Oncology in Resource-Limited Settings: Application and Early Results of Regional Educational Workshops

Raya Hamad Saab, Rihab Nasr, Iman Sidhom, Asim Belgaumi et autres

PURPOSE: The global need for training in clinical research is substantial, particularly in resource-limited settings. We describe an international collaboration to build capacity in clinical research skills through a semi-personalized curriculum. METHODS: Five sequential workshops (2020-2025) combined online modules with on-site, project-based …

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Highlights From the 2025 Pediatric Oncology East and Mediterranean Biennial Conference: Advancing Pediatric Oncology Across the Eastern Mediterranean

Rawad Rihani, Sima C. Jeha, Luham Abu Rashida, Farah Ghamloush et autres

PURPOSE: The Pediatric Oncology East and Mediterranean (POEM) Biennial Conference serves as a regional platform to advance childhood cancer care through scientific exchange, collaborative research, capacity building, and policy engagement. The 2025 Fourth Scientific Meeting aimed to showcase regional innovations, strengthen partnerships, …

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List of contributors

Sara Abudahab, Ola AlAzzeh, Lucia Altucci, Jesper Bøje Andersen et autres

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Pharmacoepigenetic considerations for the treatment of breast cancer

T. Eldika, Rihab Nasr, N.K. Zgheib

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CircRNAs and miRNAs: Key Player Duo in Breast Cancer Dynamics and Biomarkers for Breast Cancer Early Detection and Prevention

Nour Maatouk, Abdallah Kurdi, Sarah Marei, Rihab Nasr et autres

Breast cancer (BC) remains a significant global health issue, necessitating advanced molecular approaches for early detection and prevention. This review delves into the roles of microRNAs (miRNAs) and circular RNAs (circRNAs) in BC, highlighting their potential as non-invasive biomarkers. Utilizing in silico …

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123P The gut microbiome: A potential modulator of patient prognosis in colorectal cancer

Sally Naji Temraz, Farah J. Nassar, R. Altartir, M. Mezher et autres

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Abstract 2987: microRNA (miRNA) a putative biomarker to better define the molecular apocrine breast cancer (MABC) subtype

Ghada Chamandi, Adrien Borgel, Abdallah Kurdi, Pierre Khoueiry et autres

Abstract Background: Breast cancer (BC), is a highly heterogeneous disease, divided into molecular subtypes based on gene expression and clinical outcomes. Transcriptomics profiling depicted a subtype that has luminal expression profile but lacks estrogen receptor (ER), progesterone receptor expression with an overlapping …

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Abstract 1054: Reciprocal circRNA-miRNA expression axes indicative of early tumor initiation in breast

Nour Maatouk, Sarah Marei, Abdallah Bilal Kurdi, Nadim Shady Hamade et autres

Abstract Cancer prevention and early detection are the most effective tools for cancer control. In this study, we adopt a novel approach of identifying a network of proteins/mRNA-circRNA-miRNA axes. We hypothesize that mutation of oncogenes or tumor suppressor genes during pre-oncogenic stage …

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The molecular signature of BCR::ABLP210 and BCR::ABLT315I in a Drosophila melanogaster chronic myeloid leukemia model

Amro Baassiri, Ali Ghais, Abdallah Kurdi, Elias A. Rahal et autres

Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder resulting from a balanced translocation leading to BCR::ABL1 oncogene with increased tyrosine kinase activity. Despite the advancements in the development of tyrosine kinase inhibitors (TKIs), the T315I gatekeeper point mutation in …

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Evaluating synergistic effects of metformin and simvastatin on ovarian cancer cells

Sara Mikhael, Abdallah Kurdi, Nathalie Khoueiry Zgheib, Roula Tahtouh et autres

BACKGROUND: Ovarian Cancer (OC) stands as the most lethal gynecological malignancy, presenting an urgent clinical challenge in the quest to improve response rates. One approach to address this challenge is through drug repurposing, exemplified by the investigation of metabolic-modulating drugs such as …

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Evaluating the academic scientific laboratories' safety by applying failure mode and effect analysis (FMEA) at the public university in Lebanon

Inaam Nasrallah, Ibtissam Sabbah, Chadia Haddad, Lina A. Ismaiil et autres

Workers at scientific academic laboratories are at risk of potential exposure to different types of hazards. The study's purpose was to assess the potential failure modes (FMs) of hazards facing them through the application of the Failure Mode and Effect Analysis (FMEA) …

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