Michael Stich

De novo synthesis of infectious bacteriophage MS2 labelled with dyes: Investigation of the electrical properties of its interior

Natalya A. Vodolazkaya, Iryna Budzanivska, Volodymyr Farafonov, О. В. Бондаренко et autres

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Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

Josep Maria Ribó, Isabel Herreros, David Hochberg, Federico Morán et autres

ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid/base pairs was simulated using a simple “toy” model. Membrane semi‐permeability and selective passive diffusion lead to internal stationary states that inevitably exhibit electroneutrality breaking. The resulting …

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Fitness Effect of the Isoniazid Resistance Mutation S315T of the Catalase-Peroxidase Enzyme KatG of Mycobacterium tuberculosis

Ugo Bastolla, Mikhail Rotkevich, Miguel Arenas, Manuel Arrayás et autres

The mutation S315T of the catalase-peroxidase (CP) protein KatG of Mycobacterium tuberculosis is the most common mutation that confers resistance to the prodrug isoniazid. Here, we reconstruct its evolutionary history in 145 whole-genome sequences of M. tuberculosis from Russian hospitals, inferring 11 …

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In Memoriam: David Hochberg February 3, 1957–December 30, 2023

Celia Blanco, Thomas Buhse, Pedro Cintas, Isabel Herreros et autres

Elixhauser comorbidity method in predicting death of Spanish inpatients with asplenia and pneumococcal pneumonia

Enrique Gea–Izquierdo, Rossana Ruiz-Urbaez, Valentín Hernández‐Barrera, Michael Stich et autres

BACKGROUND: Pneumococcal pneumonia (PP) is a serious infection caused by Streptococcus pneumoniae (pneumococcus), with a wide spectrum of clinical manifestations. The aim of this study was to analyze the comorbidity factors that influenced the mortality in patients with asplenia according to PP. …

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Complete Virion Simulated: All-Atom Model of an MS2 Bacteriophage with Native Genome

Vladimir S. Farafonov, Michael Stich, Dmitry Nerukh

For the first time, a complete all-atom molecular dynamics (MD) model of a virus, bacteriophage MS2, in its entirety, including a protein outer shell, native genomic RNA with necessary divalent ions, and surrounding explicit aqueous solution with ions at physiological concentration, was …

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Influence of various colloidal surfactants on the stability of MS2 bacteriophage suspension. The charge distribution on the PCV2 virus surface

Natalya A. Vodolazkaya, Anna Laguta, Vladimir S. Farafonov, Marina Nikolskaya et autres

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A biphasic model of lifespan in nematode Caenorhabditis elegans worm

Suhayl Mulla, Adele Ludlam, Aiman Elragig, Cathy Slack et autres

Ageing research focuses on identifying lifespan modifiers and understanding and appropriately interpreting their effects. One of the most relevant quantities being studied is the shape of the survival curve that can reveal crucial information on the mechanism of action. Here, we introduce …

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Raw worm data RSOS from A biphasic model of lifespan in nematode Caenorhabditis elegans worm

Suhayl Mulla, Adele Ludlam, Aiman Elragig, Cathy Slack et autres

The file contains all raw data pertaining to the worm experiments.

Raw fly data RSOS from A biphasic model of lifespan in nematode Caenorhabditis elegans worm

Suhayl Mulla, Adele Ludlam, Aiman Elragig, Cathy Slack et autres

The file contains all raw data pertaining to the fly experiments.

(Digital Presentation) Electrodeposition of Free-Standing Porous Cu Frameworks for Energy Applications

Mario Kurniawan, Jasmin Calmbach, Kosovare Zullufi, Michael Stich et autres

Recently, a convenient method has been suggested to produce a highly porous metal structure such as Cu using a single-step electrodeposition method [1]. In this approach, hydrogen bubbles are used as dynamic templates during the metal electrodeposition process to create the micro-porous …

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Estimation of Nanoparticle’s Surface Electrostatic Potential in Solution Using Acid–Base Molecular Probes. III. Experimental Hydrophobicity/Hydrophilicity and Charge Distribution of MS2 Virus Surface

Natalya A. Vodolazkaya, Marina Nikolskaya, Anna Laguta, Vladimir S. Farafonov et autres

MS2 bacteriophage is often used as a model for evaluating pathogenic viruses’ behavior in aqueous solution. However, the questions of the virus surface’s hydrophilic/hydrophobic balance, the charge distribution, and the binding mechanism are open. Using the dynamic light scattering method and laser …

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