Accès ouvert
2025
article
OpenAlex
Ann-Marie Hellerung Christiansen, Kathrine Vauvert Römmelmayer Hviid, Anna J. M. Aabakke, Eva R. Hoffmann et autres
Passive maternal-fetal transfer of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies has been demonstrated, whilst the degree of transfer depending on the trimester of infection is lacking. Due to neonates' immature immune systems, this knowledge could be of interest when investigating …
dk
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Accès ouvert
2025
article
OpenAlex
Michelle K. Y. Seah, Yuyuan Han, Yan Huang, A Staübli et autres
PR/SET domain-containing (PRDM) proteins are metazoan-specific transcriptional regulators that play diverse roles in mammalian development and disease. Several members such as PRDM1, PRDM14 and PRDM9, have been implicated in germ cell specification and homoeostasis and are essential to fertility-related processes. Others, such …
sg, dk, us
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Accès ouvert
2022
conference-abstract
OpenAlex
Alejandro Coroleu Montserrat Ferrer, A Pujol, Judith Bello-Rodríguez, A Rodríguez et autres
Abstract Study question Is Cadherin1 required for human embryo blastulation? Summary answer Knock-out of Cadherin1 by Crispr/Cas9 technology in human embryos impairs cavitation and blastula stability. What is known already Embryo compaction involves an increase in intracellular adhesion mediated by E-cadherin. Concomitantly, …
es, dk
(code pays fourni par la source)
2021
article
OpenAlex
Nina la Cour Freiesleben, Pia Egerup, Kathrine Vauvert Römmelmayer Hviid, Elin Rosenbek Severinsen et autres
(Abstracted from Hum Reprod 2021;36(1):40–47) Pregnant women are at an increased risk of viral infections and increased risk of serious morbidity such as severe pneumonia, particularly during the first trimester. COVID-19 (coronavirus disease 2019) is caused by severe acute respiratory syndrome coronavirus …
dk, de
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Accès ouvert
2020
article
OpenAlex
Nina la Cour Freiesleben, Pia Egerup, Kathrine Vauvert Römmelmayer Hviid, Elin Rosenbek Severinsen et autres
STUDY QUESTION: Does maternal infection with severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) in first trimester pregnancy have an impact on the fetal development as measured by nuchal translucency thickness and pregnancy loss? SUMMARY ANSWER: Nuchal translucency thickness at the first trimester scan …
dk
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Accès ouvert
2020
article
OpenAlex
Pia Egerup, Line Fich Olsen, Ann-Marie Hellerung Christiansen, David Westergaard et autres
OBJECTIVE: To investigate the frequency of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in parturient women, their partners, and their newborns and the association of such antibodies with obstetric and neonatal outcomes. METHODS: From April 4 to July 3, 2020, in …
dk
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Accès ouvert
2020
preprint
OpenAlex
Pia Egerup, Line Fich Olsen, Ann-Marie Hellerung Christiansen, David Westergaard et autres
Abstract Background Only few studies have focused on serological testing for SARS-CoV-2 in pregnant women and no previous study has investigated the frequency in partners. The aim was to investigate the frequency and impact of SARS-CoV-2 in parturient women, their partners and …
dk
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Nina la Cour Freiesleben, Pia Egerup, Kathrine Vauvert Römmelmayer Hviid, Elin Rosenbek Severinsen et autres
Abstract Background Several viral infections are known to be harmful to the fetus in the first trimester of pregnancy and can cause increased nuchal translucency thickness and pregnancy loss. Currently, no evidence exists regarding possible effects of SARS-CoV-2 in first trimester pregnancies. …
dk
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Accès ouvert
2019
article
OpenAlex
Covadonga Vara, Laia Capilla, Luca Ferretti, Alice Ledda et autres
One of the major challenges in evolutionary biology is the identification of the genetic basis of postzygotic reproductive isolation. Given its pivotal role in this process, here we explore the drivers that may account for the evolutionary dynamics of the PRDM9 gene …
es, gb, mx, pt, us
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