Augusto Afonso Guerra

Pricing of innovative medicines and advanced therapies worldwide: an scoping review

Roberto Lúcio Muniz Júnior, Vanessa Souza Pinto, Francisco de Assis Acúrcio, Augusto Afonso Guerra et autres

Pricing policies may contribute to improving patient access to medicines. Innovative Medicines and Advanced Therapies represent promising treatment options; however, their high costs and limited clinical evidence pose both clinical and financial risks. In many cases, prices do not reflect the actual …

br (code pays fourni par la source)

Uso de Cannabis e Síndrome de Down: uma revisão de escopo sobre anomalias congênitas e trissomia do 21

Camila Santos Pires, Mariana Dias Lula, Manuelle Natividade, Marina Nascimento Silva et autres

Introdução: A síndrome de Down foi inicialmente descrita por John Langdon Down em 1866, sendo posteriormente associada à trissomia do cromossomo 21 graças aos avanços da citogenética promovidos por Lejeune, Gautier e Turpin. Essa aneuploidia constitui a alteração cromossômica mais comum nas …

br (code pays fourni par la source)

The Pharmaceutical Innovativeness Index: Supporting Value-Based Economic Regulation of Innovative Medicines

Ludmila Peres Gargano, Marcus Carvalho Borin, Wallace Mateus Prata, Juliana Álvares-Teodoro et autres

The regulation of new medicine prices must balance financial sustainability with equitable access to innovation. Value-Based Pricing (VBP) strategies seek to align drug prices with their clinical and societal impact. The Pharmaceutical Innovativeness Index (PII) is a transparent and reproducible tool proposed …

br, us (code pays fourni par la source)

EPH185 Predictors of Effectiveness of Biologic and Targeted Synthetic Disease Modifying Antirheumatic Drugs in the Treatment of Rheumatoid Arthritis

Natália Dias Brandão, Marina Garcia, Bárbara Rodrigues Alvernaz dos Santos, Francisco de Assis Acúrcio et autres

br (code pays fourni par la source)

EPH179 Pharmacovigilance of Cannabis-Based Products in Brazil

Mariana Dias Lula, Ronaldo Portela, M.L. Silva, Augusto Afonso Guerra et autres

br, fr (code pays fourni par la source)

EE107 Budget Impact of Including Cannabis-Based Products in Brazil’s Public Health System: A Scenario Analysis

Mariana Dias Lula, Ludmila Peres Gargano, Maria Laura Silva, Augusto Afonso Guerra et autres

br, fr (code pays fourni par la source)

Overall survival of neoadjuvant versus adjuvant systemic treatment for breast cancer in Brazil

Carolina Zampirolli Dias, Carolina Sousa, Thais Piazza, Ilka Afonso Reis et autres

OBJECTIVE: Compare the overall survival of women with non-metastatic breast cancer who received neoadjuvant systemic therapy followed by surgery versus those who underwent surgery followed by adjuvant systemic therapy. METHODS: A nationwide retrospective cohort study was conducted using real-world data from 2008 …

br, Sao Tomé-et-Principe (code pays fourni par la source)

Pharmaceutical access in Brazil: challenges and opportunities

Cristina Mariano Ruas, Ronaldo Portela, Francisco de Assis Acúrcio, Augusto Afonso Guerra et autres

BACKGROUND: Brazil faces challenges in ensuring equitable access to prescription drugs for its population. Socioeconomic disparities contribute to health inequalities, impacting access to health care services, including medicines. Brazil's Unified Health System aims to provide universal health care coverage, but only 30·5% …

br, us (code pays fourni par la source)

Space pharmacopeia and AI: Designing a comprehensive and proactive AI healthcare management tool for short-term space missions

Devjoy Dev, Alavia Batool, Zuzanna Pasko, Onder Bakir et autres

us, pk, tr, br (code pays fourni par la source)

Applying the Efficiency Frontier to Inform Value-Based Pricing for Gaucher Disease Therapies in Brazil

Marcus Carvalho Borin, Ludmila Peres Gargano, Francisco de Assis Acúrcio, Juliana Lopes Teodoro et autres

Background: Gaucher Disease (GD) is a rare genetic disorder characterized by visceral and hematological clinical manifestations. Various therapeutic options are currently available, all associated with high costs to the healthcare system, requiring rigorous economic evaluations to support decisions on the incorporation and …

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Uncovering DENV, CHIKV, and ZIKV in Urban Wastewater in Brazil Through Genomic and Molecular Screening

Juliana Calábria de Araújo, Ana Paula Assad Carvalho, Talita Adelino, Felipe Campos de Melo Iani et autres

This study evaluated and compared molecular methods for the detection of arboviruses Dengue (DENV), Chikungunya (CHIKV), and Zika (ZIKV) in wastewaters collected from July 2022 to May 2023 in the region of Belo Horizonte, Brazil. Detection rates varied substantially across the methods. …

br, Afrique du Sud, it, Sao Tomé-et-Principe (code pays fourni par la source)

not-yet-known not-yet-known not-yet-known unknown THE PHARMACEUTICAL INNOVATIVENESS INDEX: SUPPORTING VALUE-BASED ECONOMIC REGULATION OF INNOVATIVE MEDICINES

Ludmila Peres Gargano, Marcus Carvalho Borin, Wallace Mateus Prata, Juliana Lopes Teodoro et autres

not-yet-known not-yet-known not-yet-known unknown Background: The pricing regulation of new medicines must balance financial sustainability with access to innovation. Value-Based Pricing (VBP) strategies aim to align drug prices with their clinical and social impact. The Pharmaceutical Innovativeness Index (PII) is a proposed …

br (code pays fourni par la source)