Thomas Kjærgaard

Chronic obstructive sleep apnoea

Erik Hägerström, Eva Kirkegaard Kiær, Therese Ovesen, Christian von Buchwald et autres

Chronic obstructive sleep apnoea (OSA) is a common disease in Denmark but is still grossly underdiagnosed. This is concerning, as OSA predisposes to serious conditions such as hypertension, type 2 diabetes, cardiovascular disease, and early death. Awareness of OSA and identification of …

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A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

Elizabeth F. Maughan, Lei Wu, Dong Zhang, Linxiao Wu et autres

Abstract Laryngotracheal reconstruction surgery (LTR) is the standard treatment for paediatric upper airway stenosis, enabling tracheostomy decannulation, and restoration of vocalization. In complex infant cases, postoperative stenting is essential for graft integration and minimization of restenosis, yet available off‐the‐shelf stents are often …

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Surgically Based Deintensification for Oropharyngeal Cancer

Michael C. Topf, Thomas Kjærgaard, Catherine Po Ling Chan, F. Christopher Holsinger

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Failure pattern and salvage in head and neck cancer of unknown primary: A national study by DAHANCA

Signe Bergliot Nielsen, Morten Horsholt Kristensen, Anne I. S. Holm, Ruta Zukauskaite et autres

BACKGROUND: Failure patterns in patients with head and neck squamous cell carcinoma of unknown primary (HNSCCUP) depend on disease etiology and treatment type and extent. Treatment strategies may include radiotherapy to address any potential mucosal tumor sites, or alternatively, the omission of …

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Feasibility of rotational optical coherence tomography (OCT) as perioperative support during stenting procedures

Anne Poulsen, Signe Bødker Thim, Thomas Kjærgaard, Emil Nielsen Holck et autres

Central airway obstruction (COA), often associated with lung cancer, results in severe respiratory symptoms due to a blockage of the airway and thus limitation of airflow to a segment of the lungs. The condition is usually managed stenting of the affected airway …

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Surgical treatment for postpneumonectomy syndrome

Nikolaj Vestergaard Carlsen, Thomas Kjærgaard, Anette Hoejsgaard, Maninder Singh Kalkat et autres

Postpneumonectomy syndrome (PPS) is a rare complication after pneumonectomy characterised by severe mediastinal shift leading to airway compression and respiratory distress. We present a case of a woman in her mid-40s who developed PPS following a right pneumonectomy for bronchial mucoepidermoid carcinoma. …

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Surgeon-Performed Transoral Ultrasonography for Detection and Staging of Oropharyngeal Cancers

Martin Garset‐Zamani, Gitte Bjørn Hvilsom, Thomas Kjærgaard, Pádraig O’Leary et autres

Importance: Early-stage oropharyngeal squamous cell carcinoma (OPSCC) is challenging to diagnose using clinical examination and cross-sectional imaging. Ultrasonography performed transorally can provide high-resolution images of oropharyngeal structures; however, whether it improves diagnostic evaluation of patients with suspected OPSCC is unknown, and yet …

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The DAHANCA 27 Phase II Study: Transoral Laser Microsurgery for T1aN0M0 Glottic Squamous Cell Carcinoma, a Comparison to Accelerated Radiotherapy

Nina Munk Lyhne, Thomas Kjærgaard, Jesper Filtenborg Tvedskov, Christian Godballe et autres

INTRODUCTION: Endoscopic surgery of T1a glottic squamous cell carcinoma (SCC) is believed to have advantages compared to radiotherapy (RT), including short duration, cost-effectiveness, repeatability, and RT reserved for second tumors/failures. The equality of tumor control probability after treatments is unresolved. METHODS: In …

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Intraoperative methadone for postoperative pain in adult patients undergoing tonsillectomy—a randomised controlled trial

Michael Helbo Bøndergaard, Peter Uhrbrand, Tutku Karaca, Marianne Rhode et autres

Background Tonsillectomy is a common procedure often associated with severe postoperative pain. This study hypothesised that methadone would provide superior postoperative pain relief and reduced opioid consumption compared with fentanyl. Methods A total of 120 adult patients undergoing elective bilateral tonsillectomy were …

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Optical Coherence Tomography (OCT) Provides Detailed Information About the Abnormal Pediatric Airway and Improves Airway Assessment – The OCT Air Study

Anne Poulsen, Sok Thim, Thomas Kjærgaard, Emil Nielsen Holck et autres

Abstract RATIONALE Methods currently used for assessing abnormal pediatric airway methods have several limitations. Computed Tomography (CT) scans use a high dose of ionizing radiation. Additionally, CT output is not dynamic, which compromises the quality of the output. A diagnostic dynamic bronchoscopy …

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Patient-centred outcome following endoscopic management of benign central airway obstruction

Mads Bøgh, Dalia Gustaityté Larsen, Matilde Lonka, Sten Schytte et autres

PURPOSE: To examine patient-centred outcome following endoscopic treatment of central airway stenosis in terms of days alive and out of hospital (DAOH), need for re-intervention, and complications, with reference to aetiology of disease and applied treatment methodology. METHODS: Analyses were based on …

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Idiopathic subglottic stenosis in a 32-year-old pregnant woman

Bo Toennesen, Thomas Kjærgaard, Johannes Martin Schmid

Diagnosis of subglottic stenosis remains greatly a challenge for physicians due to case rarity and presentation of symptoms imitating several other more prevalent medical disorders. Idiopathic subglottic stenosis most often occurs in previously healthy perimenopausal Caucasian women. Several cases have reported symptom …

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