Maryana Savytska

Effect of supplementation with synbiotics in metabolic syndrome: mechanisms and clinical implications

Ludovico Abenavoli, Kateryna YOSYPENKO, Yuliia YURCHYSHENA, Maryana Savytska et autres

Metabolic syndrome (MetS) is a complex and multifactorial condition that represents a major global health challenge. It is characterized by a cluster of interrelated metabolic abnormalities, including central obesity, insulin resistance, dyslipidemia, and hypertension, all of which substantially increase the risk of …

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What role will physiological resilience play in brown-white fat dynamic in obesity management?

Oksana Zayachkivska, Iryna Kovalchuk, Iryna Muzyka, Maryana Savytska

The current obesity prevalence presents a significant paradox: despite notable therapeutic advances, including widespread use of GLP-1 receptor agonists (GLP-1RA) and SGLT2 inhibitors (SGLT2i) valued at $46.7 billion globally, the prevalence is expected to rise. Projections for 2035 estimate economic costs of …

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Efficacy of probiotic co-supplementation with omega-3 PUFAs on pancreatic beta-cell function in type 2 diabetes

Maryana Savytska, Dmytro Kyriienko, Galyna Mykhalchyshyn, Olena Tsyryuk et autres

The current understanding of the beneficial effects of probiotics in type 2 diabetes (T2D) relies on both animal and clinical data, which focus mainly on their impact on insulin resistance. The use of high-dose omega-3 polyunsaturated fatty acid (PUFA) therapy has been …

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SAT-419-YI A postbiotics and metabiotics reduces the hepatic steatosis indices and aminotransferase activity in MASLD patients: a randomized clinical trial (DELI_MASLD study)

Maryana Savytska, Yeva Ilkiv, Olena Baka, Еліна Манжалій et autres

BUILDING ACTIVE LEARNING IN MEDICAL EDUCATION: HOW TO BRIDGE VISION WITH REAL PRACTICE?

Youngil Chang, Iryna Kovalchuk, Maryana Savytska, Оksana Zayachkivska

Introduction: This manuscript explores the role of active learning in medical education, focusing on innovative strategies that bridge theoretical knowledge with practical skills essential for future healthcare professionals. With insights from both global and local applications, the paper highlights the implementation of …

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Efficacy and safety of postbiotic supplementation in patients with obesity/prediabetes: A randomized clinical trial (DELI_OBES study)

Maryana Savytska, Olena Baka, Еліна Манжалій, Dmytro Kyriienko et autres

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MICROFLORA OF COMBAT WOUNDS OF THE MALE PELVIC ORGANS AND DYSBACTERIOSIS OF THE URINARY SYSTEM

Oksana V. Melnyk, И В Коваленко, Mykola Z. Vorobets, V. V. Chaplyk et autres

Introduction. Identification of microorganisms that colonize combat wounds and cause wound infection is of primary importance for the subsequent successful treatment of the patient. The resistance of microorganisms to antimicrobial drugs makes the efforts of modern medicine in the fight against infectious …

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SAT-213 Postbiotic supplementation for metabolic dysfunction-associated steatotic liver disease

Maryana Savytska, Olena Baka, Еліна Манжалій, Dmytro Kyriienko et autres

Efficacy and safety of postbiotic supplementation for type 2 diabetes patients: Randomized clinical Ttrial (DELI Diab study)

Maryana Savytska, Olena Baka, Еліна Манжалій, Dmytro Kyriienko et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Probiotic co-supplementation with absorbent smectite for pancreatic beta-cell function in type 2 diabetes: a secondary-data analysis of a randomized double-blind controlled trials

Maryana Savytska, Dmytro Kyriienko, Ganna ZAYCHENKO, Danylo Ostapchenko et autres

Introduction There is growing evidence from animal and clinical studies suggesting probiotics can positively affect type 2 diabetes (T2D). In a previous randomized clinical study, we found that administering a live multistrain probiotic and absorbent smectite once a day for eight weeks …

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Accuracy of attenuation coefficient measurement (ACM) for real-time ultrasound hepatic steatometry: Comparison of simulator/phantom data with magnetic resonance imaging proton density fat fraction (MRI-PDFF)

Nazarii M. Kobyliak, Oleh Dynnyk, Maryana Savytska, Oleksandr Solodovnyk et autres

Objectives: To evaluate the accuracy and reproducibility of real time ultrasound (US) steatometry with the Attenuation Coefficient (AC) measurement in comparison with magnetic resonance imaging with proton density software module (MRI-PDFF). Methods: This study was conducted between January 2021 and October 2021. …

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Probiotic for Pancreatic β-Cell Function in Type 2 Diabetes: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

Maryana Savytska, Dmytro Kyriienko, Iuliia Komisarenko, Oleksandr I. Kovalchuk et autres

INTRODUCTION: Many clinical studies have proved the effectiveness of probiotics in metabolic disorders associated with insulin resistance. However, the impact of probiotic therapy on pancreatic β-cell function is ambiguous. The influence of probiotic supplementation vs. placebo on β-cell function in people with …

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