Richard L. Kradin

Benign Asbestos-Related Disorders of the Pleura

Richard L. Kradin

Asbestos is a generic term for six naturally occurring fibrous silicates that were used extensively in the twentieth century, primarily for their insulating properties. Following their introduction into the workplace, it was noted that a variety of benign and malignant diseases were …

Talc and Malignant Mesothelioma

Richard L. Kradin

Malignant mesothelioma is a rare malignancy of serosal-lined tissues. It has been recognized since the last century that the majority of pleural mesotheliomas are caused by exposures to asbestos, a fibrous silicate mineral that was used extensively in the construction trades for …

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Malignant Mesothelioma In Situ: A Controversial Diagnostic Entity – A Review

Richard L. Kradin

Malignant mesothelioma is a rare aggressive malignancy of serosal surfaces that is strongly associated with exposure to asbestos. The pathological diagnosis of malignant mesothelioma can be difficult to distinguish from reactive benign hyperplasia. Mutations in BAP-1 and CDKN2a distinguish mesothelioma from reactive …

Bacterial, Parasitic, and Fungal Infections of the Liver in Children

Donald A. Novak, Gregory Yves Lauwers, Richard L. Kradin

Both systemic and local infections caused by bacterial, fungal, and parasitic agents may cause significant hepatic dysfunction. This chapter will attempt to delineate clinical syndromes caused by some of these organisms in the pediatric patient.

Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor‐1 and neuroendocrine markers

Yin Pun Hung, Athena L. Chen, Martin S. Taylor, Tiffany G. Huynh et autres

AIMS: Nuclear protein in testis (NUT) carcinoma, an aggressive tumour driven by NUTM1 rearrangements, often involves the lung/mediastinum and shows squamous differentiation. We encountered an index patient with a thoracic NUT carcinoma diagnosed by molecular testing, showing extensive pleural involvement and diffuse …

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Endobronchial Optical Coherence Tomography for In Vivo Microscopic Diagnosis of Pulmonary Fibrosis

Lida P. Hariri, Sreyankar Nandy, Benjamin W. Roop, David C. Adams et autres

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Authors' response to “malignant mesothelioma following exposure to cosmetic talc: Association, not causation”

Theresa S. Emory, John C. Maddox, Richard L. Kradin

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Malignant mesothelioma following repeated exposures to cosmetic talc: A case series of 75 patients

Theresa S. Emory, John C. Maddox, Richard L. Kradin

BACKGROUND: Asbestos is the primary known cause of malignant mesothelioma. Some cosmetic talc products have been shown to contain asbestos. Recently, repeated exposures to cosmetic talc have been implicated as a cause of mesothelioma. METHODS: Seventy-five individuals (64 females; 11 males) with …

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In vivo diagnosis of idiopathic pulmonary fibrosis (IPF) using endobronchial OCT (Conference Presentation)

Sreyankar Nandy, Benjamin W. Roop, David C. Adams, Ashok Muniappan et autres

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive form of interstitial lung disease (ILD). High-resolution CT (HRCT) is currently used to identify macroscopic IPF features. However, for 50% of patients, ultimate diagnosis relies on microscopic features from invasive, high-risk surgical biopsies (SLBX). …

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Judaism and Christianity in Freudian Psychology

Richard L. Kradin

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Judaism and Christianity in Jungian Psychology

Richard L. Kradin

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“Have You Seen My Servant Job?” A Psychological Approach to Suffering

Richard L. Kradin