Søren Persson

A broader perspective on antimicrobial resistance in food chains

Kåre Mølbak, Anders Rhod Larsen, Ute Wolff Sönksen, Lance B. Price et autres

Researchers and decision makers repeatedly highlight the need to apply a holistic approach in the fight against antimicrobial resistance (AMR). Nonetheless, current systems for surveillance of AMR in foodborne infections tend to prioritize outbreak-detectable microbial agents. This underestimates foodborne transmission of antimicrobial-resistant …

dk, us (code pays fourni par la source)

A Single Amino Acid Substitution in CspA Increases Germination Sensitivity and Broadens Bile Salt Germinant Specificity in Clostridioides difficile Spores

Isabel Roseiro, Alexandra Nunes, Diogo Martins, Frederico Alves et autres

Once regarded primarily as a healthcare-associated pathogen, Clostridioides difficile has increasingly been reported as a cause of community-acquired infection, raising questions about the contribution of animal and environmental reservoirs to persistence and transmission. Ribotype 033 (RT033) is predominantly associated with animal and …

pt, dk (code pays fourni par la source)

Comparison of Illumina and Oxford Nanopore sequencing data quality for Clostridioides difficile genome analysis and their application for epidemiological surveillance

Semeh Bejaoui, Sofie Nielsen, Astrid Rasmussen, John Coia et autres

BACKGROUND: The burden of Clostridioides difficile as a nosocomial- and community-acquired pathogen has been increasing over the recent decades, including reports of severe outbreaks. Molecular and virulence genotyping are central for the epidemiological surveillance of this pathogen, but need to balance accuracy …

dk, ch (code pays fourni par la source)

Genomic study of European Clostridioides difficile ribotype 002/sequence type 8

Ines Dost, Mostafa Y. Abdel‐Glil, Søren Persson, Karen Loaiza Conza et autres

Clostridioides difficile has significant clinical importance as a leading cause of healthcare-associated infections, with symptoms ranging from mild diarrhoea to severe colitis, and possible life-threatening complications. C. difficile ribotype (RT) 002, mainly associated with MLST sequence type (ST) 8, is one of …

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D-JRP15-FED-AMR-WP2.1 FINAL REPORT

Werner Ruppitsch, Adriana Cabal Rosel, Brandtner Martin, Markus Wögerbauer et autres

OHEJP Project: FED-AMR (Final Report)

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Final report JRP15-AMR2.1-FED-AMR

Adriana Cabal Rosel, Krista Rathammer, Nadine Peischl, Manuela Caniça et autres

current version of the final report of the FED-AMR project

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Deliverable D-JRP15–FED-AMR-WP3.2: Overview of genetic overlap between human and non-human Clostridiodes difficile isolates

Mónica Oleastro, Søren Persson, Christian Seyboldt, Ines Dost et autres

This deliverable and the associated task aims to contribute to increase knowledge regarding the true impact of C. difficile as a zoonotic agent and its transmission networks, by evaluating the extent of genetic overlap and potential transmission between human and non-human C. …

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Sentinel surveillance and epidemiology of Clostridioides difficile in Denmark, 2016 to 2019

Søren Persson, Hans Linde Nielsen, John Coia, Jørgen Engberg et autres

Background Since 2008, Danish national surveillance of Clostridioides difficile has focused on binary toxin-positive strains in order to monitor epidemic types such as PCR ribotype (RT) 027 and 078. Additional surveillance is needed to provide a more unbiased representation of all strains …

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Dogs are carriers of Clostridioides difficile lineages associated with human community-acquired infections

Olivia Graaf Bjöersdorff, Sanna Lindberg, Kristoffer Kiil, Søren Persson et autres

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Molecular diagnostics of Salmonella and Campylobacter in human/animal fecal samples remain feasible after long-term sample storage without specific requirements

CB Harder, Søren Persson, J. Christensen, Andrea Ljubić et autres

Rapid advances in the development of sequencing technologies, numbers of commercial providers and diminishing costs have made DNA-based identification and diagnostics increasingly accessible to doctors and laboratories, eliminating the need for local investments in expensive technology and training or hiring of skilled …

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Towards standards for human fecal sample processing in metagenomic studies

Paul Igor Costea, Georg Zeller, Shinichi Sunagawa, Éric Pelletier et autres

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Towards diagnostic metagenomics of Campylobacter in fecal samples

Sandra Christine Andersen, Kristoffer Kiil, Christoffer Bugge Harder, Mathilde H. Josefsen et autres

The development of diagnostic metagenomics is driven by the need for universal, culture-independent methods for detection and characterization of pathogens to substitute the time-consuming, organism-specific, and often culture-based laboratory procedures for epidemiological source-tracing. Some of the challenges in diagnostic metagenomics are, that …

dk (code pays fourni par la source)