Larysa Zhuravlyova

Systemic manifestations of porphyria cutanea tarda against the background of liver cirrhosis: literature review and case report

Larysa Zhuravlyova, Yu.K. Sikalo, V. O. Fedorov, A. K. Zhuravlyova et autres

Porphyria cutanea tarda (PCT) is a metabolic disorder caused by a deficiency in uroporphyrinogen decarboxylase, leading to systemic porphyrin deposition. The diagnosis of PCT in the setting of decompensated liver cirrhosis is significantly challenging due to clinical mimicry of systemic connective tissue …

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Transthoracic echocardiography in emergency settings: FoCUS protocol

Larysa Zhuravlyova, O. O. Yankevych, Tetyana Rogachova

Transthoracic echocardiography was previously exclusively the domain of ultrasound physicians, which created delays in clinical decision‑making. Cardiologists, intensive care physicians, and physicians of other specialties depended on the conclusions of ultrasound specialists, which created significant inconveniences, including delays in obtaining diagnostic information. …

САРКОПЕНІЯ У ПАЦІЄНТІВ ІЗ ЦУКРОВИМ ДІАБЕТОМ 2 ТИПУ: СУЧАСНІ ДІАГНОСТИЧНІ КРИТЕРІЇ, МЕХАНІЗМИ РОЗВИТКУ ТА СТРАТЕГІЇ ЛІКУВАННЯ

Larysa Zhuravlyova, Олена Михайлівна Кривоносова, A. K. Zhuravlyova

Цукровий діабет 2 типу є одним із найпоширеніших метаболічних захворювань у світі, що суттєво впливає на якість і тривалість життя, особливо серед літніх людей. У статті розглядається взаємозв’язок між цукровим діабетом 2 типу та саркопенією – віковим дегенеративним станом, що характеризується втратою …

Exocrine pancreatic insufficiency in the setting of chronic heart failure with reduced ejection fraction: mechanisms of development and approaches to their correction. Review

Larysa Zhuravlyova, Tetyana Rogachova, O.O. Yankevich, Maryna Filonenko

The aim of this review is to discuss the available evidence on the mechanisms of development of exocrine pancreatic insufficiency in chronic heart failure with reduced ejection fraction, their clinical consequences and modern ways of correction. The results of modern studies have …

THE EFFECT OF DAPAGLIFLOZIN ON BLOOD PRESSURE IN ELDERLY PATIENTS WITH OBESITY, ARTERIAL HYPERTENSION AND POORLY CONTROLLED TYPE 2 DIABETES

Larysa Zhuravlyova, Tetyana Rogachova, Maryna Filonenko, O. O. Yankevych et autres

Objective: To evaluate the effect of dapagliflozin (D) versus metformin (M) on blood pressure (BP) and glycaemic control in elderly patients with obesity, arterial hypertension (AH), and poorly controlled type 2 diabetes mellitus (T2DM), in addition to standard antihypertensive therapy. Design and …

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Managing a patient with rapidly progressive methotrexate-resistant localized scleroderma (morphea). Clinical case

Larysa Zhuravlyova, Yu.K. Sikalo, V. O. Fedorov, Татьяна Ивановна Ховрат et autres

Localized scleroderma (Morphea) is a chronic autoimmune connective tissue disease characterized by fibrosis of the skin and underlying tissues, which may lead to disability and cosmetic problems. The disease usually lacks systemic manifestations such as internal organ involvement, Raynaud’s phenomenon, or telangiectasia. …

Cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus. Review

Larysa Zhuravlyova, Tetyana Rogachova, O.O. Yankevich

According to the data, obtained in 2024, type 2 diabetes mellitus affects 8% of the global population, totaling 400 million patients worldwide. Cardiovascular autonomic neuropathy is a very common but underestimated complication of type 2 diabetes, occurring in 60% of cases. It …

Rheumatoid arthritis and viral hepatitis. Tactics of a rheumatologist. Literature review

Larysa Zhuravlyova, Mariia Oliinyk, Yu.K. Sikalo, V. O. Fedorov

Rheumatoid arthritis (RA) is an autoimmune disease that can be accompanied by complex liver involvement. The diagnosis and differentiation of these conditions are often complicated by the rarity of liver biopsies and the similarity of symptoms to other liver diseases. Viral hepatitis …

THE ROLE OF ASPROSIN IN LIPID METABOLISM IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND CHRONIC PANCREATITIS

Larysa Zhuravlyova, Mykyta A. Markevych

Background. Type 2 Diabetes Mellitus (T2DM) is a highly prevalent metabolic disease that significantly affects patients' quality of life and increases mortality due to complications. Understanding the relationships between T2DM and chronic pancreatitis (CP) is very important, as both conditions significantly impact …

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Exocrine pancreatic insufficiency in diabetes

Larysa Zhuravlyova, Tetyana Rogachova

One of the underestimated complications of diabetes is exocrine pancreatic insufficiency (EPI). The consequences of EPI in patients with diabetes include malabsorption syndrome and its complications: deficiencies of fat-soluble vitamins A, D, E, and K, osteoporosis, sarcopenia, and increased overall mortality, which …

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Impact of asprosin, interleukin-6, and adiponectin on exocrine pancreatic insufficiency in patients with type 2 diabetes mellitus and chronic pancreatitis

Larysa Zhuravlyova, Mykyta A. Markevych

Exocrine pancreatic insufficiency (EPI) is a clinical condition often associated with chronic pancreatitis (CP) and type 2 diabetes mellitus (T2DM) leads to malabsorption and nutritional deficiencies, severely impacting patients’ quality of life. It has been identified that asprosin, a glucogenic protein, is …

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Determination of asprosin levels and analysis of correlative relationships with carbohydrate metabolism indicators in patients with type 2 diabetes and chronic pancreatitis

Larysa Zhuravlyova, Mykyta A. Markevych

Objective — to investigate asprosin levels in patients with type 2 diabetes mellitus (DM) and chronic pancreatitis (CP) and to analyze the correlations between asprosin levels and carbohydrate metabolism indicators in these patients. Materials and methods. The study was conducted on 100 …