Accès ouvert
2022
article
OpenAlex
Tina Haase, Christian Müller, Bastian Stoffers, Philipp Kirn et autres
Beyond the influence of lifestyle-related risk factors for myocardial infarction (MI), the mechanisms of genetic predispositions for MI remain unclear. We sought to identify and characterize differentially expressed genes in early-onset MI in a translational approach. In an observational case−control study, transcriptomes …
de, us, se
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Accès ouvert
2021
article
OpenAlex
Hanna Bräuninger, Tilo Thottakara, Jacob Schön, Svenja Voss et autres
Fibroblasts contribute to approximately 20% of the non-cardiomyocytic cells in the heart. They play important roles in the myocardial adaption to stretch, inflammation, and other pathophysiological conditions. Fibroblasts are a major source of extracellular matrix (ECM) proteins whose production is regulated by …
de, gb
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Accès ouvert
2019
article
OpenAlex
Svenja Voss, Saskia Krüger, Katharina Scherschel, Svenja Warnke et autres
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine known to play a major role in inflammatory diseases such as myocardial infarction (MI), where its expression increases. Cardio protective functions of MIF during ischemia have been reported. Recently, the structurally related MIF-2 …
de
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