Lisa M. Schumaker

Preliminary Development and Assessment of a Multiplex Assay for Human Papillomavirus Antibody Detection Using Commercial L1 Proteins

Arash Aslanabadi, Maryam Karimi, Laura Powell, Lisa M. Schumaker et autres

BACKGROUND: Human papillomavirus (HPV)-associated cancers are preventable with vaccination. Serologic assays monitor antibody responses, but their complexity and cost pose limitations when evaluating population level immunity. We developed an L1-based assay for the detection of multiple type-specific HPV antibodies. METHODS: The Luminex-based …

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Impact of Radiomics Parameters and Clinical Integration on Prognostication in Head and Neck Squamous Cell Carcinoma: A Multicenter Study

Hajar Moradmand, Jason Molitoris, Ranee Mehra, Lisa M. Schumaker et autres

Radiomics has the potential to improve risk stratification in head and neck squamous cell carcinoma (HNSCC), but clinical adoption is limited by inconsistent performance across institutions. A key source of variability is how radiomic features are generated, preprocessed, and selected prior to …

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Oral human papillomavirus and HIV: A cross-sectional study among men with same-sex sexual contact in Nigeria

Kareshma Mohanty, Connor Volpi, Kehinde Akinyombo, Chinenye Mgbakogu et autres

BackgroundOropharyngeal cancers associated with oral human papillomavirus (oHPV) are becoming more common. Understanding factors associated with oHPV among African men, including those living in settings where broader contextual factors shape how HPV-associated cancers are prioritized, may help predict future cancer risk and …

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AI-Driven Graph-Based Radiomics: Enhancing Imaging Biomarkers Reproducibility in Multi-Institutional Head and Neck Cancer Management

Hajar Moradmand, Jason K. Molitoris, Lisa M. Schumaker, Erin Allor et autres

Graph feature selection for enhancing radiomic stability and reproducibility across multiple institutions in head and neck cancer

Hajar Moradmand, Jason K. Molitoris, Ling Xiao, Lisa M. Schumaker et autres

Radiomic biomarkers offer promise for precision oncology. However, their clinical utility is limited by variability from differing imaging protocols and the high dimensionality of radiomics data. Feature selection is key for better interpretability, accuracy, and efficiency, yet traditional methods lack stability and …

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Penile human papillomavirus prevalence in circumcised sexual minority men with and without HIV

Nginache Nampota-Nkomba, Kareshma Mohanty, Ruxton Adebiyi, Charles Ekeh et autres

OBJECTIVE: Understanding the burden of penile human papillomavirus (HPV) among high-risk groups is essential to inform tailored prevention strategies to reduce HPV-related morbidity. We estimated the prevalence of penile HPV and its association with HIV among circumcised sexual minority men (SMM). DESIGN: …

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Author Correction: Identification of CT based radiomic biomarkers for progression free survival in head and neck squamous cell carcinoma

Ling Xiao, Soha Bazyar, Matthew J. Ferris, Jason K. Molitoris et autres

“Xiao Ling and Lei Ren were supported by the National Institutes of Health (NIH) grants R01EB032680 and U54CA273956. Daria A. Gaykalova was supported by a Research Scholarship Grant, RSG-21-020-01-MPC from the American Cancer Society, and R01DE027809 from the National Institute of Health.”

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Identification of CT based radiomic biomarkers for progression free survival in head and neck squamous cell carcinoma

Ling Xiao, Soha Bazyar, Matthew J. Ferris, Jason K. Molitoris et autres

This study addresses the limited noninvasive tools for Head and Neck Squamous Cell Carcinoma (HNSCC) progression-free survival (PFS) prediction by identifying Computed Tomography (CT)-based biomarkers for predicting prognosis. A retrospective analysis was conducted on data from 203 HNSCC patients. An ensemble feature …

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Identification of CT-based Radiomic Biomarkers for Progression-Free Survival in Head and Neck Squamous Cell Carcinoma

Ling Xiao, Soha Bazyar, Matthew J. Ferris, Jason K. Molitoris et autres

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CT-Based Radiomic Biomarkers for Predicting Progression-Free Survival in Head and Neck Squamous Cell Carcinoma

Xuefeng B. Ling, Soha Bazyar, Matthew J. Ferris, J.K. Molitoris et autres

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Radiomic biomarkers of locoregional recurrence: prognostic insights from oral cavity squamous cell carcinoma preoperative CT scans

Ling Xiao, Gregory S. Alexander, Jason K. Molitoris, Jin‐Hyuk Choi et autres

Introduction: This study aimed to identify CT-based imaging biomarkers for locoregional recurrence (LR) in Oral Cavity Squamous Cell Carcinoma (OSCC) patients. Methods: Computed tomography scans were collected from 78 patients with OSCC who underwent surgical treatment at a single medical center. We …

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Radiomic Biomarkers of Locoregional Recurrence: Prognostic Insights from Oral Cavity Squamous Cell Carcinoma preoperative CT scans

Lei Ren, Ling Xiao, Gregory S. Alexander, Jason K. Molitoris et autres

This study aimed to identify CT-based imaging biomarkers for locoregional recurrence (LR) in Oral Cavity Squamous Cell Carcinoma (OSCC) patients. Our study involved a retrospective review of 78 patients with OSCC who underwent surgical treatment at a single medical center. An approach …

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