Accès ouvert
2026
book-chapter
OpenAlex
Maryam Moradpour, Zully Ritter, Anne-Christin Hauschild
INTRODUCTION: Class imbalance can hinder reliable detection of clinically relevant outcomes in binary clinical prediction. In this study, the positive class was predefined as the clinically relevant minority outcome; therefore, accuracy-only hyperparameter selection can favor the majority class and reduce sensitivity for …
de
(code pays fourni par la source)
Accès ouvert
2026
preprint
OpenAlex
Maryam Moradpour, Anne-Christin Hauschild
Artificial intelligence models are promising for medical diagnosis, but they require large numbers of unbiased data, which in medicine are distributed across hospitals and cannot be centralized to protect patient privacy. Federated Learning (FL) addresses this, since hospitals train one shared diagnostic …
Accès ouvert
2026
preprint
OpenAlex
Julia Schirmacher, M. Mäurer, Jacqueline Michelle Metsch, Hryhorii Chereda et autres
Abstract Motivation Graph Neural Networks (GNNs) have gained increasing interest in the biomedical domain, as the integration of prior knowledge and deep neural networks has the potential to enhance insights into molecular processes and disease mechanisms. However, a comprehensive and systematic assessment …
de
(code pays fourni par la source)
Accès ouvert
2026
preprint
OpenAlex
Nghiem Vo, Anh-Tien Nguyen, Thong N. H. Vo, Ga-Yeon Yang et autres
kr, de, us, sk
(code pays fourni par la source)
2026
conference-paper
OpenAlex
Maryam Moradpour, Anne-Christin Hauschild
de
(code pays fourni par la source)
Accès ouvert
2026
book-chapter
OpenAlex
Linus Weber, Anne-Christin Hauschild, Michael Altenbuchinger, Ulrich Sax et autres
A common challenge in Federated Learning (FL) is that distribution shifts between clients, or Non-IIDness, decrease global model performance. Non-IIDness means that data is not independently and identically distributed between participating sites. Stronger distributional shifts lead to greater reductions of model performance. …
de, dk
(code pays fourni par la source)
Accès ouvert
2026
book-chapter
OpenAlex
Zully Ritter, M. Mäurer, Jacqueline Michelle Metsch, Lisa Weller et autres
Machine learning (ML) has great potential in healthcare, especially with large structured data. Routine health insurance claims (HIC) data are a valuable resource, comprising standardized longitudinal patient information. However, to fully leverage ML in HIC, challenges such as large data volumes, variability, …
de
(code pays fourni par la source)
Accès ouvert
2026
preprint
OpenAlex
Maryam Moradpour, Jonas Harriehausen, Amirreza Aleyasin, Lion Philipp Wolf et autres
Multi-center survival prediction can improve robustness and generalizability, yet privacy regulations and institutional governance often prevent pooling patient-level clinical and genomic data across institutions. In practice, deployment is further complicated by feature-space heterogeneity, in which sites collect different covariates or use different …
Accès ouvert
2026
preprint
OpenAlex
Maryam Moradpour, Jonas Harriehausen, Amirreza Aleyasin, Lion Philipp Wolf et autres
Multi-center survival prediction can improve robustness and generalizability, yet privacy regulations and institutional governance often prevent pooling patient-level clinical and genomic data across institutions. In practice, deployment is further complicated by feature-space heterogeneity, in which sites collect different covariates or use different …
us, de
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Anne-Christin Hauschild, Amirreza Aleyasin, Nils Beyer, Lisa Fricke et autres
Introduction: Ideally, centrally collecting and analyzing patient data with appropriate consent would provide optimal data quality and predictive performance; however, this approach is often not feasible in practice. Federated Learning (FL) or Federated Artificial Intelligence architectures have shown [for full text, please …
de
(code pays fourni par la source)
Accès ouvert
2026
conference-paper
OpenAlex
Zully Ritter, M. Mäurer, Jacqueline Michelle Beinecke, Lisa Weller et autres
Introduction: The use of artificial intelligence, particularly machine learning models, to develop predictive models from health insurance routine data is becoming increasingly common [ref:1], [ref:2]. However, it’s not always clear when and how to leverage the advantages [for full text, please go …
de, gb
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
M. Mäurer, P. Hempel, Kristin Steinhaus, Hryhorii Chereda et autres
The clinical deployment of artificial intelligence (AI) solutions for assessing cardiovascular disease (CVD) risk in 12-lead electrocardiography (ECG) is hindered by limitations in interpretability and explainability. To address this, we present xGNN4MI, an open-source framework for graph neural networks (GNNs) in ECG …
de, dk
(code pays fourni par la source)