Máté Nagy‐Pénzes

OGG1 Inhibition Reduces Acinar Cell Injury in a Mouse Model of Acute Pancreatitis

Zoltán Hajnády, Máté Nagy‐Pénzes, Máté Ágoston Demény, Katalin Éva Kovács et autres

Acute pancreatitis (AP) is a potentially life-threatening gastrointestinal disease with a complex pathology including oxidative stress. Oxidative stress triggers oxidative DNA lesions such as formation of 7,8-dihydro-8-oxo-2'-oxoguanine (8-oxoG) and also causes DNA strand breaks. DNA breaks can activate the nuclear enzyme poly(ADP-ribose) …

hu, Égypte (code pays fourni par la source)

Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein-Induced Acute Pancreatitis: The Role of Oxidative Stress-Induced DNA Damage Signaling

Máté Nagy‐Pénzes, Zoltán Hajnády, Zsolt Regdon, Máté Ágoston Demény et autres

Acute pancreatitis (AP) poses a worldwide challenge due to the growing incidence and its potentially life-threatening course and complications. Specific targeted therapies are not available, prompting the identification of new pathways and novel therapeutic approaches. Flavonoids comprise several groups of biologically active …

hu, Égypte (code pays fourni par la source)

OGG1 in AP

Zoltán Hajnády, Máté Nagy‐Pénzes, Máté Ágoston Demény, Katalin Éva Kovács et autres

The file contains data supporting our findings reported in the manuscript titled "OGG1 inhibition reduces acinar cell injury in a mouse model of acute pancreatitis" accepted for publication in "Biomedicines"..

hu (code pays fourni par la source)

OGG1 in AP

Zoltán Hajnády, Máté Nagy‐Pénzes, Máté Ágoston Demény, Katalin Éva Kovács et autres

The file contains data supporting our findings reported in the manuscript titled "OGG1 inhibition reduces acinar cell injury in a mouse model of acute pancreatitis" accepted for publication in "Biomedicines"..

hu (code pays fourni par la source)

Mate Nagy-Penzes et al TCT in AP

Máté Nagy‐Pénzes, Zoltán Hajnádi, Zsolt Regdon, Máté Ágoston Demény et autres

Primary data supporting findings reported in Nagy Penzes et al. on the effect of TCT in AP

hu (code pays fourni par la source)

Mate Nagy-Penzes et al TCT in AP

Máté Nagy‐Pénzes, Zoltán Hajnádi, Zsolt Regdon, Máté Ágoston Demény et autres

Primary data supporting findings reported in Nagy Penzes et al. on the effect of TCT in AP

hu (code pays fourni par la source)

Poly(ADP-Ribose) Polymerase 1 Promotes Inflammation and Fibrosis in a Mouse Model of Chronic Pancreatitis

Tarek El‐Hamoly, Zoltán Hajnády, Máté Nagy‐Pénzes, Edina Bakondi et autres

Chronic pancreatitis (CP) is an inflammatory disease of the pancreas characterized by ductal obstructions, tissue fibrosis, atrophy and exocrine and endocrine pancreatic insufficiency. However, our understanding is very limited concerning the disease's progression from a single acute inflammation, via recurrent acute pancreatitis …

hu, Égypte (code pays fourni par la source)

IJMS primary data CP.xlsx

Tarek El‐Hamoly, Zoltán Hajnády, Máté Nagy‐Pénzes, Edina Bakondi et autres

These data were used for the Research Paper titled "Poly(ADP-Ribose) Polymerase 1 Promotes Inflammation and Fibrosis in a Mouse Model of Chronic Pancreatitis" which has been accepted for publication in the journal IJMS. Methodologies, techniques, etc ar e described in the paper.

High‐content screening identifies inhibitors of oxidative stress‐induced parthanatos: cytoprotective and anti‐inflammatory effects of ciclopirox

Zsolt Regdon, Máté Ágoston Demény, Katalin Éva Kovács, Zoltán Hajnády et autres

Background and Purpose Excessive oxidative stress can induce PARP1‐mediated programmed necrotic cell death, termed parthanatos. Inhibition of parthanatos may be therapeutically beneficial in a wide array of diseases associated with tissue injury and inflammation. Our goal was to identify novel molecules inhibiting …

hu (code pays fourni par la source)

Spilanthol Inhibits Inflammatory Transcription Factors and iNOS Expression in Macrophages and Exerts Anti-inflammatory Effects in Dermatitis and Pancreatitis

Edina Bakondi, Salam Bhopen Singh, Zoltán Hajnády, Máté Nagy‐Pénzes et autres

Activated macrophages upregulate inducible nitric oxide synthase (iNOS) leading to the profuse production of nitric oxide (NO) and, eventually, tissue damage. Using macrophage NO production as a biochemical marker of inflammation, we tested different parts (flower, leaf, and stem) of the medicinal …

hu (code pays fourni par la source)